Recombinant Human FTO Protein, His-tagged FTO-14H

Recombinant Human FTO Protein, His-tagged

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Recombinant Human FTO Protein, His-tagged

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Cat.No. : FTO-14H
Product Overview : Recombinant human FTO protein (32-505) with a N-terminal His-tag was expressed in E. coli.
Description : This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes.
Source : E. coli
Species : Human
Tag : His
Form : 50 mM HEPES, pH 8.0, with 150 mM sodium choride and 10% glycerol
Molecular Mass : 56.68 kDa
Protein length : 32-505
Purity : ≥80% estimated by SDS-PAGE
Applications : WB
Stability : ≥ 1 year
Storage : Store at -80 centigrade
SDS-PAGE of FTO :

Lane 1: MW Markers, Lane 2: FTO (4 µg), Lane 3: FTO (2 µg). Representative gel image shown; actual purity may vary between each batch.

Gene Name : FTO FTO alpha-ketoglutarate dependent dioxygenase [ Homo sapiens (human) ]
Official Symbol : FTO
Synonyms : FTO; FTO alpha-ketoglutarate dependent dioxygenase; GDFD; ALKBH9; BMIQ14; alpha-ketoglutarate-dependent dioxygenase FTO; AlkB homolog 9; U6 small nuclear RNA (2'-O-methyladenosine-N(6)-)-demethylase FTO; U6 small nuclear RNA N(6)-methyladenosine-demethylase FTO; fat mass and obesity associated; fat mass and obesity-associated protein; m6A(m)-demethylase FTO; mRNA (2'-O-methyladenosine-N(6)-)-demethylase FTO; mRNA N(6)-methyladenosine demethylase FTO; tRNA N1-methyl adenine demethylase FTO
Gene ID : 79068
mRNA Refseq : NM_001080432
Protein Refseq : NP_001073901
MIM : 610966
UniProt ID : Q9C0B1

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