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Recombinant Human GAD2 Protein, Myc/DDK-tagged, C13 and N15-labeled
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| Cat.No. : | GAD2-4173H |
| Product Overview : | GAD2 MS Standard C13 and N15-labeled recombinant protein (NP_000809) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
| Description : | This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. |
| Source : | HEK293 |
| Species : | Human |
| Tag : | Myc/DDK |
| Molecular Mass : | 65.4 kDa |
| AA Sequence : | MASPGSGFWS FGSEDGSGDS ENPGTARAWC QVAQKFTGGI GNKLCALLYG DAEKPAESGG SQPPRAAARK AACACDQKPC SCSKVDVNYA FLHATDLLPA CDGERPTLAF LQDVMNILLQ YVVKSFDRST KVIDFHYPNE LLQEYNWELA DQPQNLEEIL MHCQTTLKYA IKTGHPRYFN QLSTGLDMVG LAADWLTSTA NTNMFTYEIA PVFVLLEYVT LKKMREIIGW PGGSGDGIFS PGGAISNMYA MMIARFKMFP EVKEKGMAAL PRLIAFTSEH SHFSLKKGAA ALGIGTDSVI LIKCDERGKM IPSDLERRIL EAKQKGFVPF LVSATAGTTV YGAFDPLLAV ADICKKYKIW MHVDAAWGGG LLMSRKHKWK LSGVERANSV TWNPHKMMGV PLQCSALLVR EEGLMQNCNQ MHASYLFQQD KHYDLSYDTG DKALQCGRHV DVFKLWLMWR AKGTTGFEAH VDKCLELAEY LYNIIKNREG YEMVFDGKPQ HTNVCFWYIP PSLRTLEDNE ERMSRLSKVA PVIKARMMEY GTTMVSYQPL GDKVNFFRMV ISNPAATHQD IDFLIEEIER LGQDLSGPTR TRPLEQKLIS EEDLAANDIL DYKDDDDKV |
| Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : | 50 μg/mL as determined by BCA |
| Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
| SDS-PAGE : |
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| Gene Name : | GAD2 glutamate decarboxylase 2 [ Homo sapiens (human) ] |
| Official Symbol : | GAD2 |
| Synonyms : | GAD2; glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa); glutamate decarboxylase 2 (pancreatic islets and brain, 65kD); glutamate decarboxylase 2; GAD65; GAD-65; 65 kDa glutamic acid decarboxylase; Glutamate decarboxylase-2 (pancreas); glutamate decarboxylase 65 kDa isoform; MGC161605; MGC161607; |
| Gene ID : | 2572 |
| mRNA Refseq : | NM_000818 |
| Protein Refseq : | NP_000809 |
| MIM : | 138275 |
| UniProt ID : | Q05329 |
◆ Recombinant Protein
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| GAD2-512M | Recombinant Mouse GAD2 Protein (1-585 aa), His-tagged | +Inquiry |
| Gad2-860M | Recombinant Mouse Gad2, His & GST tagged | +Inquiry |
| Gad2-6736R | Recombinant Rat Gad2 protein, His-tagged | +Inquiry |
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◆ Lysates
| GAD2-001MCL | Recombinant Mouse GAD2 cell lysate | +Inquiry |
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