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Recombinant Human GCKR Protein, MYC/DDK-tagged

Cat.No. : GCKR-660H
Product Overview : Recombinant Human GCKR fused with MYC/DDK tag at C-terminal was expressed in HEK293.
Description : This gene encodes a protein belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY).
Source : HEK293
Species : Human
Tag : MYC/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass : 68.5 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : GCKR glucokinase (hexokinase 4) regulator [ Homo sapiens ]
Official Symbol : GCKR
Synonyms : GCKR; glucokinase (hexokinase 4) regulator; glucokinase (hexokinase 4) regulatory protein; glucokinase regulatory protein; GKRP; FGQTL5;
Gene ID : 2646
mRNA Refseq : NM_001486
Protein Refseq : NP_001477
MIM : 600842
UniProt ID : Q14397

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