Recombinant Human GFRAL protein, His-Avi-tagged GFRAL-60H

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Recombinant Human GFRAL protein, His-Avi-tagged

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Cat.No. :	GFRAL-60H
Product Overview :	Human LILRA3 Protein is expressed from mammalian with His and Avi Tag at the C-terminal. It contains Gly24-Glu439.
Description :	GFR alpha -like (GDNF receptor-alpha-like) is a distant member of the GDNFR family of proteins. Mature human GFR alpha-like is a 376 amino acid (aa) type I transmembrane protein. It contains a 333 aa extracellular domain, a 20 aa transmembrane domain and a 23 aa cytoplasmic domain. GFRAL is a brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses.
Source :	HEK293
Species :	Human
Tag :	His-Avi
Form :	Supplied as 0. 22um filtered solution in 20mM PB, 300mM NaCl (pH 6. 5).
Molecular Mass :	The protein has a predicted MW of 40. 7 kDa. Due to glycosylation, the protein migrates to 48-62KDa based on Bis-Tris PAGE result.
Protein length :	Gly24-Glu439
Endotoxin :	Less than 0. 1EU per ug by the LAL method.
Purity :	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Storage :	The product should be stored at -70°C. Please do not repeated freeze-thaw cycles.
Reconstitution :	It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4ºC before opening to recover the entire contents.
Tris-Bis PAGE :
SEC-HPLC :
ELISA data :

Gene Name :	GFRAL GDNF family receptor alpha like [ Homo sapiens ]
Official Symbol :	GFRAL
Synonyms :	GFR alpha like; GFR alpha-like; GFRAL; GRAL; GDNF family receptor alpha-lik; C6orf144
Gene ID :	389400
mRNA Refseq :	NM_207410. 2
Protein Refseq :	NP_997293. 2
MIM :	617837
UniProt ID :	Q6UXV0