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Recombinant Human GFRAL protein, His-tagged

Cat.No. : GFRAL-002H
Product Overview : Recombinant Human GFRAL protein (Ser19-Glu351) was fused to His-tag at C-terminus and expressed in human 293 cells (HEK293).
  • Specification
  • Gene Information
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Description : Brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses. Upon interaction with its ligand, GDF15, interacts with RET and induces cellular signaling through activation of MAPK- and AKT- signaling pathways.
Source : HEK293
Species : Human
Tag : His
Molecular Mass : The predicted molecular mass is 38 kDa, and the actual MW is about 40 kDa in SDS-PAGE under reducing conditions.
Protein length : 333
Endotoxin : <1 EU/mg as determined by LAL test.
Purity : >80%,by SDS-PAGE under reducing conditions.
Gene Name : GFRAL
Official Symbol : GFRAL
Synonyms : GRAL; UNQ9356; C6orf144; bA360D14.1
Gene ID : 389400
mRNA Refseq : NM_207410.2
Protein Refseq : NP_997293.2
MIM : 617837
UniProt ID : Q6UXV0

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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