Recombinant Human GFRAL protein, His-tagged GFRAL-002H

Recombinant Human GFRAL protein, His-tagged

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Recombinant Human GFRAL protein, His-tagged

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Cat.No. : GFRAL-002H
Product Overview : Recombinant Human GFRAL protein (Ser19-Glu351) was fused to His-tag at C-terminus and expressed in human 293 cells (HEK293).
Description : Brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses. Upon interaction with its ligand, GDF15, interacts with RET and induces cellular signaling through activation of MAPK- and AKT- signaling pathways.
Source : HEK293
Species : Human
Tag : His
Molecular Mass : The predicted molecular mass is 38 kDa, and the actual MW is about 40 kDa in SDS-PAGE under reducing conditions.
Protein length : 333
Endotoxin : <1 EU/mg as determined by LAL test.
Purity : >80%,by SDS-PAGE under reducing conditions.
SDS-PAGE of GFRAL-002H :

Gene Name : GFRAL
Official Symbol : GFRAL
Synonyms : GRAL; UNQ9356; C6orf144; bA360D14.1
Gene ID : 389400
mRNA Refseq : NM_207410.2
Protein Refseq : NP_997293.2
MIM : 617837
UniProt ID : Q6UXV0

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