Recombinant Human GFRAL Protein, His-tagged

• Cat.No.: GFRAL-22H
• Product Overview: Recombinant protein of human GDNF family receptor alpha like (GFRAL), with C-terminal His tag, secretory expressed in Sf9 cells.

Specification

• Description: Brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses. Upon interaction with its ligand, GDF15, interacts with RET and induces cellular signaling through activation of MAPK- and AKT- signaling pathways.
• Source: Insect cell
• Species: Human
• Tag: His
• Molecular Mass: 37.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Storage: Store at -80 centigrade after receiving vials. Stable for at least 3 months from receipt of products under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 50 mM Tris.HCl, pH 8.0, 150 mM glycine, 10% glycerol.

Gene Information

• Gene Name: GFRAL GDNF family receptor alpha like [ Homo sapiens (human) ]
• Official Symbol: GFRAL
• Synonyms: GFRAL; GDNF family receptor alpha like; GRAL; UNQ9356; C6orf144; bA360D14.1; GDNF family receptor alpha-like; IVFI9356
• Gene ID: 389400
• mRNA Refseq: NM_207410
• Protein Refseq: NP_997293
• MIM: 617837
• UniProt ID: Q6UXV0