| Description : |
This gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
117.9 kDa |
| AA Sequence : |
MFNSMTPPPISSYGEPCCLRPLPSQ GAPSVGTEGLSGPPFCHQANLMSGP HSYGPARETNSCTEGPLFSSPRSAV KLTKKRALSISPLSDASLDLQTVIR TSPSSLVAFINSRCTSPGGSYGHLS IGTMSPSLGFPAQMNHQKGPSPSFG VQPCGPHDSARGGMIPHPQSRGPFP TCQLKSELDMLVGKCREEPLEGDMS SPNSTGIQDPLLGMLDGREDLEREE KREPESVYETDCRWDGCSQEFDSQE QLVHHINSEHIHGERKEFVCHWGGC SRELRPFKAQYMLVVHMRRHTGEKP HKCTFEGCRKSYSRLENLKTHLRSH TGEKPYMCEHEGCSKAFSNASDRAK HQNRTHSNEKPYVCKLPGCTKRYTD PSSLRKHVKTVHGPDAHVTKRHRGD GPLPRAPSISTVEPKREREGGPIRE ESRLTVPEGAMKPQPSPGAQSSCSS DHSPAGSAANTDSGVEMTGNAGGST EDLSSLDEGPCIAGTGLSTLRRLEN LRLDQLHQLRPIGTRGLKLPSLSHT GTTVSRRVGPPVSLERRSSSSSSIS SAYTVSRRSSLASPFPPGSPPENGA SSLPGLMPAQHYLLRARYASARGGG TSPTAASSLDRIGGLPMPPWRSRAE YPGYNPNAGVTRRASDPAQAADRPA PARVQRFKSLGCVHTPPTVAGGGQN FDPYLPTSVYSPQPPSITENAAMDA RGLQEEPEVGTSMVGSGLNPYMDFP PTDTLGYGGPEGAAAEPYGARGPGS LPLGPGPPTNYGPNPCPQQASYPDP TQETWGEFPSHSGLYPGPKALGGTY SQCPRLEHYGQVQVKPEQGCPVGSD STGLAPCLNAHPSEGPPHPQPLFSH YPQPSPPQYLQSGPYTQPPPDYLPS EPRPCLDFDSPTHSTGQLKAQLVCN YVQSQQELLWEGGGREDAPAQEPSY QSPKFLGGSQVSPSRAKAPVNTYGP GFGPNLPNHKSGSYPTPSPCHENFV VGANRASHRAAAPPRLLPPLPTCYG PLKVGGTNPSCGHPEVGRLGGGPAL YPPPEGQVCNPLDSLDLDNTQLDFV AILDEPQGLSPPPSHDQRGSSGHTP PPSGPPNMAVGNMSVLLRSLPGETE FLNSSATRTRPLEQKLISEEDLAAN DILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
