Recombinant Human GNA11 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human GNA11 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. : GNA11-3785H
Product Overview : GNA11 MS Standard C13 and N15-labeled recombinant protein (NP_002058) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : The protein encoded by this gene belongs to the family of guanine nucleotide-binding proteins (G proteins), which function as modulators or transducers in various transmembrane signaling systems. G proteins are composed of 3 units: alpha, beta and gamma. This gene encodes one of the alpha subunits (subunit alpha-11). Mutations in this gene have been associated with hypocalciuric hypercalcemia type II (HHC2) and hypocalcemia dominant 2 (HYPOC2). Patients with HHC2 and HYPOC2 exhibit decreased or increased sensitivity, respectively, to changes in extracellular calcium concentrations.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 42.1 kDa
AA Sequence : MTLESMMACC LSDEVKESKR INAEIEKQLR RDKRDARREL KLLLLGTGES GKSTFIKQMR IIHGAGYSEE DKRGFTKLVY QNIFTAMQAM IRAMETLKIL YKYEQNKANA LLIREVDVEK VTTFEHQYVS AIKTLWEDPG IQECYDRRRE YQLSDSAKYY LTDVDRIATL GYLPTQQDVL RVRVPTTGII EYPFDLENII FRMVDVGGQR SERRKWIHCF ENVTSIMFLV ALSEYDQVLV ESDNENRMEE SKALFRTIIT YPWFQNSSVI LFLNKKDLLE DKILYSHLVD YFPEFDGPQR DAQAAREFIL KMFVDLNPDS DKIIYSHFTC ATDTENIRFV FAAVKDTILQ LNLKEYNLVT RTRPLEQKLI SEEDLAANDI LDYKDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : GNA11 G protein subunit alpha 11 [ Homo sapiens (human) ]
Official Symbol : GNA11
Synonyms : guanine nucleotide binding protein (G protein), alpha 11 (Gq class); 4379; Ensembl:ENSG00000088256; guanine nucleotide-binding protein subunit alpha-11;g alpha-11;G-protein subunit alpha-11;guanine nucleotide-binding protein, Gq class, GNA11;guanine nucleotide-binding protein G(y) subunit alpha; GNA-11
Gene ID : 2767
mRNA Refseq : NM_002067
Protein Refseq : NP_002058
MIM : 139313
UniProt ID : P29992

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