Recombinant Human GNLY Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: GNLY-1101H
• Product Overview: GNLY MS Standard C13 and N15-labeled recombinant protein (NP_006424) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: The product of this gene is a member of the saposin-like protein (SAPLIP) family and is located in the cytotoxic granules of T cells, which are released upon antigen stimulation. This protein is present in cytotoxic granules of cytotoxic T lymphocytes and natural killer cells, and it has antimicrobial activity against M. tuberculosis and other organisms. Alternatively spliced transcript variants encoding different isoforms have been identified.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 16.4 kDa
• AA Sequence: MATWALLLLAAMLLGNPGLVFSRLS PEYYDLARAHLRDEEKSCPCLAQEG PQGDLLTKTQELGRDYRTCLTIVQK LKKMVDKPTQRSVSNAATRVCRTGR SRWRDVCRNFMRRYQSRVTQGLVAG ETAQQICEDLRLCIPSTGPLTRTRP LEQKLISEEDLAANDILDYKDDDDK V
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: GNLY granulysin [ Homo sapiens (human) ]
• Official Symbol: GNLY
• Synonyms: GNLY; granulysin; LAG2; D2S69E; LAG 2; NKG5; T lymphocyte activation gene 519; TLA519; lymphokine LAG-2; lymphocyte-activation gene 2; T-cell activation protein 519; T-lymphocyte activation gene 519; 519; LAG-2
• Gene ID: 10578
• mRNA Refseq: NM_006433
• Protein Refseq: NP_006424
• MIM: 188855
• UniProt ID: P22749