Recombinant Human GRB14 Protein, MYC/DDK-tagged

• Cat.No.: GRB14-538H
• Product Overview: Recombinant protein of human growth factor receptor-bound protein 14 (GRB14) with C-MYC/DDK tag was expressed in HEK293T cells.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. This protein likely has an inhibitory effect on receptor tyrosine kinase signaling and, in particular, on insulin receptor signaling. This gene may play a role in signaling pathways that regulate growth and metabolism. Alternative splicing results in multiple transcript variants.
• Molecular Mass: 60.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at –80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: >50 ug/mL
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: GRB14
• Official Symbol: GRB14 growth factor receptor bound protein 14 [ Homo sapiens (human) ]
• Synonyms: GRB14; growth factor receptor bound protein 14; growth factor receptor-bound protein 14; GRB14 adapter protein
• Gene ID: 2888
• mRNA Refseq: NM_004490
• Protein Refseq: NP_004481
• MIM: 601524
• UniProt ID: Q14449