| Description : |
The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. This protein likely has an inhibitory effect on receptor tyrosine kinase signaling and, in particular, on insulin receptor signaling. This gene may play a role in signaling pathways that regulate growth and metabolism. Alternative splicing results in multiple transcript variants. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
61 kDa |
| AA Sequence : |
MTTSLQDGQSAASRAAARDSPLAAQ VCGAAQGRGDAHDLAPAPWLHARAL LPLPDGTRGCAADRRKKKDLDVPEM PSIPNPFPELCCSPFTSVLSADLFP KANSRKKQVIKVYSEDETSRALDVP SDITARDVCQLLILKNHYIDDHSWT LFEHLPHIGVERTIEDHELVIEVLS NWGIEEENKLYFRKNYAKYEFFKNP MYFFPEHMVSFATETNGEISPTQIL QMFLSSSTYPEIHGFLHAKEQGKKS WKKIYFFLRRSGLYFSTKGTSKEPR HLQFFSEFGNSDIYVSLAGKKKHGA PTNYGFCFKPNKAGGPRDLKMLCAE EEQSRTCWVTAIRLLKYGMQLYQNY MHPYQGRSGCSSQSISPMRSISENS LVAMDFSGQKSRVIENPTEALSVAV EEGLAWRKKGCLRLGTHGSPTASSQ SSATNMAIHRSQPWFHHKISRDEAQ RLIIQQGLVDGVFLVRDSQSNPKTF VLSMSHGQKIKHFQIIPVEDDGEMF HTLDDGHTRFTDLIQLVEFYQLNKG VLPCKLKHYCARIALTRTRPLEQKL ISEEDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
