Recombinant Human GSK3A Protein, MYC/DDK-tagged, C13 and N15-labeled

• Cat.No.: GSK3A-055H
• Product Overview: GSK3A MS Standard C13 and N15-labeled recombinant protein (NP_063937) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a multifunctional Ser/Thr protein kinase that is implicated in the control of several regulatory proteins including glycogen synthase, and transcription factors, such as JUN. It also plays a role in the WNT and PI3K signaling pathways, as well as regulates the production of beta-amyloid peptides associated with Alzheimer's disease.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 51 kDa
• AA Sequence: MSGGGPSGGGPGGSGRARTSSFAEP GGGGGGGGGGPGGSASGPGGTGGGK ASVGAMGGGVGASSSGGGPGGSGGG GSGGPGAGTSFPPPGVKLGRDSGKV TTVVATLGQGPERSQEVAYTDIKVI GNGSFGVVYQARLAETRELVAIKKV LQDKRFKNRELQIMRKLDHCNIVRL RYFFYSSGEKKDELYLNLVLEYVPE TVYRVARHFTKAKLTIPILYVKVYM YQLFRSLAYIHSQGVCHRDIKPQNL LVDPDTAVLKLCDFGSAKQLVRGEP NVSYICSRYYRAPELIFGATDYTSS IDVWSAGCVLAELLLGQPIFPGDSG VDQLVEIIKVLGTPTREQIREMNPN YTEFKFPQIKAHPWTKVFKSRTPPE AIALCSSLLEYTPSSRLSPLEACAH SFFDELRCLGTQLPNNRPLPPLFNF SAGELSIQPSLNAILIPPHLRSPAG TTTLTPSSQALTETPTSSDWQSTDA TPTLTNSSTRTRPLEQKLISEEDLA ANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: GSK3A glycogen synthase kinase 3 alpha [ Homo sapiens (human) ]
• Official Symbol: GSK3A
• Synonyms: GSK3A; glycogen synthase kinase 3 alpha; DKFZp686D0638; glycogen synthase kinase-3 alpha; GSK-3 alpha; serine/threonine-protein kinase GSK3A; EC 2.7.11.1; EC 2.7.11.26
• Gene ID: 2931
• mRNA Refseq: NM_019884
• Protein Refseq: NP_063937
• MIM: 606784
• UniProt ID: P49840