Recombinant Human HDAC2 Protein, His-tagged HDAC2-47H

Recombinant Human HDAC2 Protein, His-tagged

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Recombinant Human HDAC2 Protein, His-tagged

HDAC2 Related Products

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Cat.No. : HDAC2-47H
Product Overview : Recombinant human HDAC2 protein with a C-terminal His-tag was expressed in baculovirus expression vector system.
Description : This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Alternative splicing results in multiple transcript variants.
Source : Insect cells
Species : Human
Tag : His
Molecular Mass : 56 kDa
Purity : ≥90% estimated by SDS-PAGE
Unit Definition : One unit is the amount of enzyme required to release 1 pmol of acetate per minute at 37 centigrade in 25 mM Tris-HCl, pH 8.0, with 137 mM sodium chloride, 2.7 mM potassium chloride, 1 mM magnesium chloride, 0.1 mg/mL BSA, and 20 μM fluorogenic HDAC substrate 3.
Applications : Enzyme Activity, WB, ELISA
Stability : ≥ 6 months
Storage : Store it at -80 centigrade
Storage Buffer : 40 mM Tris-HCl, pH 8.0, with 110 mM sodium chloride, 2.2 mM potassium chloride, 20% glycerol, and 200 mM imidazole
SDS-PAGE Analysis of HDAC2 :

Lane 1: MW Markers; Lane 2: HDAC2 (7 μg). Representative gel image shown; actual purity may vary between each batch.

HDAC2 Deacetylase Activity :

Gene Name : HDAC2 histone deacetylase 2 [ Homo sapiens (human) ]
Official Symbol : HDAC2
Synonyms : HDAC2; histone deacetylase 2; HD2; RPD3; YAF1; KDAC2; histone deacetylase 2; YY1-associated factor 1; transcriptional regulator homolog RPD3
Gene ID : 3066
mRNA Refseq : NM_001527
Protein Refseq : NP_001518
MIM : 605164
UniProt ID : Q92769

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