Recombinant Human HDAC8 Protein, GST-tagged

• Cat.No.: HDAC8-4650H
• Product Overview: Human HDAC8 full-length ORF ( AAH50433, 1 a.a. - 377 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 66.99 kDa
• AA Sequence: MEEPEEPADSGQSLVPVYIYSPEYV SMCDSPAKIPKRASMVHSLIEAYAL HKQMRIVKPKVASMEEMATFHTDAY LQHLQKVSQEGDDDHPDSIEYGLGY DCPATEGIFDYAAAIGGATITAAQC LIDGMCKVAINWSGGWHHAKKDEAS GFCYLNDAVLGILRLRRKFERILYV DLDLHHGDGVEDAFSFTSKVMTVSL HKFSPGFFPGTGDVSDVGLGKGRYY SVNVPIQDGIQDEKYYQICESVLKE VYQAFNPKAVVLQLGADTIAGDPMC SFNMTPVGIGKCLKYILQWQLATLI LGGGGYNLANTARCWTYLTGVILGK TLSSEIPDHEFFTAYGPDYVLEITP SCRPDRNEPHRIQQILNYIKGNLKH VV
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -8 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: HDAC8 histone deacetylase 8 [ Homo sapiens ]
• Official Symbol: HDAC8
• Synonyms: HDAC8; histone deacetylase 8; HDACL1, histone deacetylase like 1; RPD3; histone deacetylase-like 1; HD8; CDA07; HDACL1
• Gene ID: 55869
• mRNA Refseq: NM_001166418
• Protein Refseq: NP_001159890
• MIM: 300269
• UniProt ID: Q9BY41