Recombinant Human HEMGN Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: HEMGN-4651H
• Product Overview: HEMGN MS Standard C13 and N15-labeled recombinant protein (NP_932095) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: Regulates the proliferation and differentiation of hematopoietic cells. Overexpression block the TPA-induced megakaryocytic differentiation in the K562 cell model. May also prevent cell apoptosis through the activation of the nuclear factor-kappa B (NF-kB).
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 55.3 kDa
• AA Sequence: MDLGKDQSHLKHHQTPDPHQEENHS PEVIGTWSLRNRELLRKRKAEVHEK ETSQWLFGEQKKRKQQRTGKGNRRG RKRQQNTELKVEPQPQIEKEMEKAL APIEKKTEPPGSITKVFPSVASPQK VVPEEHFSEICQESNIYQENFSEYQ EIAVQNHSSETCQHVSEPEDLSPKM YQEISVLQDNSSKICQDMKEPEDNS PNTCQVISVIQDHPFKMYQDMAKRE DLAPKMCQEAAVPKILPCPTSEDTA DLAGCSLQAYPKPDVPKGYILDTDQ NPAEPEEYNETDQGIAETEGLFPKI QEIAEPKDLSTKTHQESAEPKYLPH KTCNEIIVPKAPSHKTIQETPHSED YSIEINQETPGSEKYSPETYQEIPG LEEYSPEIYQETSQLEEYSPEIYQE TPGPEDLSTETYKNKDVPKECFPEP HQETGGPQGQDPKAHQEDAKDAYTF PQEMKEKPKEEPGIPAILNESHPEN DVYSYVLFTRTRPLEQKLISEEDLA ANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: HEMGN hemogen [ Homo sapiens (human) ]
• Official Symbol: HEMGN
• Synonyms: HEMGN; hemogen; EDAG; hemopoietic gene protein; negative differentiation regulator protein; erythroid differentiation-associated gene protein; EDAG-1
• Gene ID: 55363
• mRNA Refseq: NM_197978
• Protein Refseq: NP_932095
• MIM: 610715
• UniProt ID: Q9BXL5