| Description : |
This gene functions as a growth regulatory and tumor repressor gene. Hypermethylation or deletion of the region of this gene have been associated with tumors and the contiguous-gene syndrome, Miller-Dieker syndrome. Alternative splicing of this gene results in multiple transcript variants. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
74.3 kDa |
| AA Sequence : |
MLDTMEAPGHSRQLLLQLNNQRTKG FLCDVIIVVQNALFRAHKNVLAASS AYLKSLVVHDNLLNLDHDMVSPAVF RLVLDFIYTGRLADGAEAAAAAAVA PGAEPSLGAVLAAASYLQIPDLVAL CKKRLKRHGKYCHLRGGGGGGGGYA PYGRPGRGLRAATPVIQACYPSPVG PPPPPAAEPPSGPEAAVNTHCAELY ASGPGPAAALCASERRCSPLCGLDL SKKSPPGSAAPERPLAERELPPRPD SPPSAGPAAYKEPPLALPSLPPLPF QKLEEAAPPSDPFRGGSGSPGPEPP GRPDGPSLLYRWMKHEPGLGSYGDE LGRERGSPSERCEERGGDAAVSPGG PPLGLAPPPRYPGSLDGPGAGGDGD DYKSSSEETGSSEDPSPPGGHLEGY PCPHLAYGEPESFGDNLYVCIPCGK GFPSSEQLNAHVEAHVEEEEALYGR AEAAEVAAGAAGLGPPFGGGGDKVA GAPGGLGELLRPYRCASCDKSYKDP ATLRQHEKTHWLTRPYPCTICGKKF TQRGTMTRHMRSHLGLKPFACDACG MRFTRQYRLTEHMRIHSGEKPYECQ VCGGKFAQQRNLISHMKMHAVGGAA GAAGALAGLGGLPGVPGPDGKGKLD FPEGVFAVARLTAEQLSLKQQDKAA AAELLAQTTHFLHDPKVALESLYPL AKFTAELGLSPDKAAEVLSQGAHLA AGPDGRTIDRFSPTSGPTRTRRLEQ KLISEEDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
