Recombinant Human HIP1 protein, His & T7-tagged


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Recombinant Human HIP1 protein, His & T7-tagged

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Cat.No. : HIP1-1738H
Product Overview : Recombinant Human HIP1 aa. (Leu817~Glu1037 (Accession # O00291)) fused with N-terminal His & T7 tag was produced in E. coli cells.
Description : The product of this gene is a membrane-associated protein that functions in clathrin-mediated endocytosis and protein trafficking within the cell. The encoded protein binds to the huntingtin protein in the brain; this interaction is lost in Huntington's disease. Alternative splicing results in multiple transcript variants.
Source : E. coli
Species : Human
Tag : His & T7
Form : Freeze-dried powder
Molecular Mass : 33kDa as determined by SDS-PAGE reducing conditions.
Protein length : Leu817~Glu1037 (Accession # O00291)
Endotoxin : <1.0EU per 1ug (determined by the LAL method)
Purity : >90%
Applications : SDS-PAGE; WB; ELISA; IP.
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Storage buffer : Supplied as lyophilized form in 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5% trehalose, and preservative.
Reconstitution : Reconstitute in sterile ddH2O.
Isoelectric Point : 5

Gene Name : HIP1 huntingtin interacting protein 1 [ Homo sapiens (human) ]
Official Symbol : HIP1
Synonyms : HIP1; huntingtin interacting protein 1; SHON; HIP-I; ILWEQ; SHONbeta; SHONgamma; huntingtin-interacting protein 1; huntingtin-interacting protein I
Gene ID : 3092
mRNA Refseq : NM_001243198.2
Protein Refseq : NP_001230127.1
UniProt ID : O00291

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