Recombinant Human HLA-B protein, His/T7-tagged


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Recombinant Human HLA-B protein, His/T7-tagged

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Cat.No. : HLA-B-392H
Product Overview : Recombinant Human HLA-B(aa 26-309) fused with His/T7 tag was expressed in E. coli.
Description : HLA-B belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons.
Source : E. coli
Species : Human
Tag : His/T7
Form : Lyophilized from PBS, pH 7.4, 5% trehalose, 0.01% sarcosyl
Molecular Mass : 36.7 kDa
Purity : Greater than 95%
Storage : Store at +4 centigrade for up to 1 month, or aliquot and store at -80 centigrade for up to 12 months. Avoid repeat freeze-thaw cycles.
Reconstitution : Reconstitute in sterile PBS, pH 7.2-7.4.
Gene Name : HLA-B major histocompatibility complex, class I, B [ Homo sapiens ]
Official Symbol : HLA-B
Synonyms : HLA-B; major histocompatibility complex, class I, B; ankylosing spondylitis , AS; lymphocyte antigen; MHC class I antigen SHCHA; MHC Class I HLA heavy chain; MHC class I antigen GN00104; leukocyte antigen class I-B; MHC HLA-B cell surface glycoprotein; MHC HLA-B transmembrane glycoprotein; MHC class I antigen HLA-B heavy chain; HLA class I histocompatibility antigen, B alpha chain; AS; HLAB; SPDA1; MGC111087;
Gene ID : 3106
mRNA Refseq : NM_005514
Protein Refseq : NP_005505
UniProt ID : P01889
Chromosome Location : 6p21.3
Pathway : Adaptive Immune System, organism-specific biosystem; Allograft rejection, organism-specific biosystem; Allograft rejection, conserved biosystem; Antigen Presentation: Folding, assembly and peptide loading of class I MHC, organism-specific biosystem; Antigen processing and presentation, organism-specific biosystem; Antigen processing and presentation, conserved biosystem; Antigen processing-Cross presentation, organism-specific biosystem;
Function : MHC class I receptor activity; receptor binding;
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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