Recombinant Human HLA-DRA protein, GST-tagged
Cat.No. : | HLA-DRA-231H |
Product Overview : | Recombinant Human HLA-DRA protein(NP_061984)(24-218 aa), fused to GST tag, was expressed in E. coli. |
- Specification
- Gene Information
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Source : | E. coli |
Species : | Human |
Tag : | GST |
Form : | The purified protein was Lyophilized from sterile PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH7.4). 5 % trehalose and 5 % mannitol are added as protectant before lyophilization. |
Protein length : | 24-218 aa |
AA Sequence : | WAIKEEHVIIQAEFYLNPDQSGEFM FDFDGDEIFHVDMAKKETVWRLEEF GRFASFEAQGALANIAVDKANLEIM TKRSNYTPITNVPPEVTVLTNSPVE LREPNVLICFIDKFTPPVVNVTWLR NGKPVTTGVSETVFLPREDHLFRKF HYLPFLPSTEDVYDCRVEHWGLDEP LLKHWEFDAPSPLPETTENV |
Purity : | 85%, by SDS-PAGE with Coomassie Brilliant Blue staining. |
Storage : | Aliquot and store at -20°C to -80°C for up to 6 months. Avoid repeat freeze-thaw cycles. |
Concentration : | The purified protein was Lyophilized from sterile PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH7.4). 5 % trehalose and 5 % mannitol are added as protectant before lyophilization. |
Reconstitution : | Reconstitute at 0.25 µg/μl in 200 μl sterile water for short-term storage. Reconstitution with 200 μl 50% glycerol solution is recommended for longer term storage. |
Gene Name : | HLA-DRA major histocompatibility complex, class II, DR alpha [ Homo sapiens ] |
Official Symbol : | HLA-DRA |
Synonyms : | HLA-DRA; major histocompatibility complex, class II, DR alpha; HLA DRA1; HLA class II histocompatibility antigen, DR alpha chain; MHC class II antigen DRA; MHC cell surface glycoprotein; histocompatibility antigen HLA-DR alpha; MLRW; HLA-DRA1; FLJ51114; |
Gene ID : | 3122 |
mRNA Refseq : | NM_019111 |
Protein Refseq : | NP_061984 |
MIM : | 142860 |
UniProt ID : | P01903 |
Products Types
◆ Recombinant Protein | ||
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HLA-DRA-490H | Recombinant Human major histocompatibility complex, class II, DR alpha, His-tagged | +Inquiry |
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◆ Lysates | ||
HLA-DRA-5501HCL | Recombinant Human HLA 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionHLA-DRA protein can present tumor-associated antigen fragments to immune cells during tumor immunity, thereby activating the immune response, which is of great significance for tumor immunotherapy.
Immunohistochemistry, flow cytometry, Western blot and other techniques can be used to detect the expression level of HLA-DRA protein.
The HLA-DRA protein is mainly involved in the antigen presentation process in the immune system, mediating the antigen fragment to T cells, thereby triggering an immune response against the antigen.
There is an association between polymorphisms of HLA-DRA proteins and the occurrence of certain diseases, as different HLA-DRA genotypes may affect the effectiveness of immune responses and thus susceptibility to diseases.
Yes, due to the important role of HLA-DRA protein in the immune system, it is considered a potential immunotherapy target that can be used to improve therapeutic strategies for immune diseases.
Yes, HLA-DRA protein is associated with the occurrence and development of infectious diseases such as viral and bacterial infections because it is involved in regulating the immune response and affecting the outcome of infection.
Customer Reviews (3)
Write a reviewBoth purity and biological activity are commendable.
It provides a strong guarantee for the accuracy of the experimental results.
Wide range of applications and provides support for scientific research.
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