Recombinant Human HSD17B4 protein, MYC/DDK-tagged
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| Cat.No. : | HSD17B4-110H |
| Product Overview : | Recombinant Human HSD17B4 fused with MYC/DDK tag at C-terminal was expressed in HEK293. |
| Description : | The protein encoded by this gene is a bifunctional enzyme that is involved in the peroxisomal beta-oxidation pathway for fatty acids. It also acts as a catalyst for the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids. Defects in this gene that affect the peroxisomal fatty acid beta-oxidation activity are a cause of D-bifunctional protein deficiency (DBPD). An apparent pseudogene of this gene is present on chromosome 8. |
| Source : | HEK293 |
| Species : | Human |
| Tag : | MYC/DDK |
| Form : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
| Molecular Mass : | 79.5 kDa |
| Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Figure : |
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| Gene Name : | HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4 [ Homo sapiens ] |
| Official Symbol : | HSD17B4 |
| Synonyms : | HSD17B4; hydroxysteroid (17-beta) dehydrogenase 4; peroxisomal multifunctional enzyme type 2; 3 alpha; 7 alpha; 12 alpha trihydroxy 5 beta cholest 24 enoyl CoA hydratase; 17 beta HSD IV; 17 beta hydroxysteroid dehydrogenase 4; 17beta estradiol dehydrogenase type IV; beta hydroxyacyl dehydrogenase; beta keto reductase; D 3 hydroxyacyl CoA dehydratase; D bifunctional protein; peroxisomal; DBP; MFE 2; peroxisomal multifunctional protein 2; SDR8C1; short chain dehydrogenase/reductase family 8C; member 1; 17-beta-HSD 4; 17-beta-HSD IV; beta-keto-reductase; multifunctional protein 2; beta-hydroxyacyl dehydrogenase; D-3-hydroxyacyl-CoA dehydratase; D-bifunctional protein, peroxisomal; 17-beta-hydroxysteroid dehydrogenase 4; 17beta-estradiol dehydrogenase type IV; short chain dehydrogenase/reductase family 8C, member 1; 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase; MFE-2; MPF-2; |
| Gene ID : | 3295 |
| mRNA Refseq : | NM_000414 |
| Protein Refseq : | NP_000405 |
| MIM : | 601860 |
| UniProt ID : | P51659 |
| Chromosome Location : | 5q2 |
| Pathway : | Beta-oxidation of pristanoyl-CoA, organism-specific biosystem; Beta-oxidation of very long chain fatty acids, organism-specific biosystem; Bile acid and bile salt metabolism, organism-specific biosystem; Bile acid biosynthesis, cholesterol => cholate, organism-specific biosystem; Bile acid biosynthesis, cholesterol => cholate, conserved biosystem; |
| Function : | 3-hydroxyacyl-CoA dehydrogenase activity; 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity; estradiol 17-beta-dehydrogenase activity; isomerase activity; long-chain-enoyl-CoA hydratase activity; lyase activity; nucleotide binding; oxidoreductase activity; sterol binding; sterol transporter activity; |
◆ Recombinant Protein
| HSD17B4-1417H | Recombinant Human HSD17B4 Protein (1-736 aa), His-tagged | +Inquiry |
| HSD17B4-10487Z | Recombinant Zebrafish HSD17B4 | +Inquiry |
| HSD17B4-13960H | Recombinant Human HSD17B4, GST-tagged | +Inquiry |
| HSD17B4-109H | Recombinant Human HSD17B4, His-tagged | +Inquiry |
| HSD17B4-6503C | Recombinant Chicken HSD17B4 | +Inquiry |
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◆ Lysates
| HSD17B4-5373HCL | Recombinant Human HSD17B4 293 Cell Lysate | +Inquiry |
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HSD17B10HSD17B11HSD17B14HSD17B8HSD17B3HSD17B1HSD3B1HSD11B1HSD17B12HSD17B7HSD3B2HSD17B4HSD11B2HSD17B2HSD17B6HSD3B7HSD17B13Hsd3bHsd3b3Hsd3b4Hsd3b5Hsd3b6HSD11B1LHSD17B7P2
