"HSPB8" Related Products

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Recombinant Human HSPB8 protein, His/MBP-tagged

Cat.No.: HSPB8-165H
Product Overview: Recombinant Human HSPB8(1-145+170-196 aa) fused with His/MBP tag was expressed in E. coli.
Description: The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.
Source: E. coli
Species: Human
Tag : His/MBP
Form: Liquid in PBS
Protein length: 1-145+170-196 aa
Purity: SDS-PAGE >90%
Applications: WB Positive Control
Stability: Samples are stable for up to twelve months from date of receipt at -70ºC.
Storage: Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Gene Name: HSPB8 heat shock 22kDa protein 8 [ Homo sapiens ]
Official Symbol: HSPB8
Synonyms: HSPB8; heat shock 22kDa protein 8; heat shock 27kDa protein 8; heat shock protein beta-8; E2IG1; H11; HSP22; HspB8; protein kinase H11; alpha-crystallin C chain; E2-induced gene 1 protein; small stress protein-like protein HSP22; HMN2; CMT2L; DHMN2; HMN2A;
Gene ID: 26353
mRNA Refseq: NM_014365
Protein Refseq: NP_055180
MIM: 608014
UniProt ID: Q9UJY1

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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