"HTRA4" Related Products

Recombinant Human HTRA4 protein, His-tagged

Cat.No.: HTRA4-793H
Product Overview: Recombinant human full length HTRA4 protein was expressed in insect cells with C-terminus his tag.
Description: This gene encodes a member of the HtrA family of proteases. The encoded protein contains a putative signal peptide, an insulin growth factor binding domain, a Kazal protease inhibitor domain, a conserved trypsin domain and a PDZ domain. Based on studies on other related family members, this enzyme may function as a secreted oligomeric chaperone protease to degrade misfolded secretory proteins. Other human HtrA proteins have been implicated in arthritis, tumor suppression, unfolded stress response, apoptosis, and aging.
Source: Insect cell
Species: Human
Tag : His
Form: 0.05% Brij, 0.05% Calcium chloride, 0.79% Tris HCl, 0.88% Sodium chloride, 0.34%, pH 7.5.
Bio-activity: Proteolytic activity of this product was documented by digestion of ß- casein. 0.5 mg ß-casein/ml are completely digested by 10 µg/ml HTRA4 within 18 hours at 37 centigrade.
Molecular Mass: 52 kDa
AA Sequence: MIRPQLRTAGLGRCLLPGLLLLLVPVLWAGAEKLHTQPSCPAVCQPTRCPALPTCALGTTPVFDLCRCCRVCPAAEREVCGGAQGQPCAPGLQCLQPLRPGFPSTCGCPTLGGAVCGSDRRTYPSMCALRAENRAARRLGKVPAVPVQWGNCGDTGTRSAGPLRRNYNFIAAVVEKVAPSVVHVQLWGRLLHGSRLVPVYSGSGFIVSEDGLIITNAHVVRNQQWIEVVLQNGARYEAVVKDIDLKLDLAVIKIESNAELPVLMLGRSSDLRAGEFVVALGSPFSLQNTATAGIVSTKQRGGKELGMKDSDMDYVQIDATINYGNSGGPLVNLDGDVIGVNSLRVTDGISFAIPSDRVRQFLAEYHEHQMKGKAFSNKKYLGLQMLSLTVPLSEELKMHYPDFPDVSSGVYVCKVVEGTAAQSSGLRDHDVIVNINGKPITTTTDVVKALDSDSLSMAVLRGKDNLLLTVIPETINHHHHHH
Purity: > 70% SDS-PAGE
Storage: Store at -80 centigrade. Avoid freeze-thaw cycles.
Concentration: 0.1 mg/mL
Gene Name: HtrA serine peptidase 4 [ Homo sapiens ]
Official Symbol: HTRA4
Synonyms: HTRA4; HtrA serine peptidase 4; probable serine protease HTRA4; FLJ90724
Gene ID: 203100
mRNA Refseq: NM_153692
Protein Refseq: NP_710159
MIM: 610700
UniProt ID: P83105

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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