Recombinant Human ICA1 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human ICA1 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. : ICA1-3708H
Product Overview : ICA1 MS Standard C13 and N15-labeled recombinant protein (NP_004959) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : This gene encodes a protein with an arfaptin homology domain that is found both in the cytosol and as membrane-bound form on the Golgi complex and immature secretory granules. This protein is believed to be an autoantigen in insulin-dependent diabetes mellitus and primary Sjogren's syndrome. Several transcript variants encoding two different isoforms have been found for this gene.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 54.5 kDa
AA Sequence : MSGHKCYPWD LQDRYAQDKS VVNKMQQKYW ETKQAFIKAT GKKEDEHVVA SDADLDAKLE LFHSIQRTCL DLSKAIVLYQ KRICFLSQEE NELGKFLRSQ GFQDKTRAGK MMQATGKALC FSSQQRLALR NPLCRFHQEV ETFRHRAISD TWLTVNRMEQ CRTEYRGALL WMKDVSQELD PDLYKQMEKF RKVQTQVRLA KKNFDKLKMD VCQKVDLLGA SRCNLLSHML ATYQTTLLHF WEKTSHTMAA IHESFKGYQP YEFTTLKSLQ DPMKKLVEKE EKKKINQQES TDAAVQEPSQ LISLEEENQR KESSSFKTED GKSILSALDK GSTHTACSGP IDELLDMKSE EGACLGPVAG TPEPEGADKD DLLLLSEIFN ASSLEEGEFS KEWAAVFGDG QVKEPVPTMA LGEPDPKAQT GSGFLPSQLL DQNMKDLQAS LQEPAKAASD LTAWFSLFAD LDPLSNPDAV GKTDKEHELL NATRTRPLEQ KLISEEDLAA NDILDYKDDD DKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : ICA1 islet cell autoantigen 1 [ Homo sapiens (human) ]
Official Symbol : ICA1
Synonyms : ICA1; islet cell autoantigen 1, 69kDa; islet cell autoantigen 1 (69kD); islet cell autoantigen 1; ICAp69; p69; islet cell autoantigen p69; 69 kDa islet cell autoantigen; islet cell autoantigen 1 isoform; diabetes mellitus type I autoantigen; ICA69;
Gene ID : 3382
mRNA Refseq : NM_004968
Protein Refseq : NP_004959
MIM : 147625
UniProt ID : Q05084

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