Recombinant Human IGF1R Protein (Asp741-His935), N-His tagged
Cat.No. : | IGF1R-0921H |
Product Overview : | Recombinant Human CD221/IGF1R (Asp741-His935) fused with the N-His tag was expressed in E. coli. |
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Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | Lyophilized powder/frozen liquid |
Molecular Mass : | 24.59 kDa |
Protein Length : | Asp741-His935 |
Purity : | >90% as determined by SDS-PAGE. |
Notes : | For research use only. |
Storage : | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt. |
Storage Buffer : | 0.01M PBS, pH 7.4, 0.02% NLS |
Reconstitution : | Reconstitute in sterile water for a stock solution. |
Shipping : | They are shipped out with dry ice/blue ice unless customers require otherwise. |
Gene Name : | IGF1R insulin-like growth factor 1 receptor [ Homo sapiens (human) ] |
Official Symbol : | IGF1R |
Synonyms : | IGF1R; insulin-like growth factor 1 receptor; CD221; IGFIR; IGFR; JTK13; MGC18216; IGF-I receptor; soluble IGF1R variant 1; soluble IGF1R variant 2; insulin-like growth factor I receptor; MGC142170; MGC142172; |
Gene ID : | 3480 |
mRNA Refseq : | NM_000875 |
Protein Refseq : | NP_000866 |
MIM : | 147370 |
UniProt ID : | P08069 |
Products Types
◆ Recombinant Protein | ||
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IGF1R-2660R | Recombinant Rat IGF1R Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
IGF1R-2928HCL | Recombinant Human IGF1R cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-1600 | IGF1R Functional Assay Kit | +Inquiry |
Kit-1601 | HEK 293 IGF1R Bioassay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Customer Reviews (3)
Write a reviewThe product's exceptional purity facilitated precise quantification, ensuring data consistency.
The product consistently delivered robust and dependable results, affirming its efficacy in our experiments.
The product's consistent performance bolstered the dependability of our research conclusions.
Q&As (7)
Ask a questionIGF1R is predominantly localized on the cell membrane, where it acts as a receptor for insulin-like growth factors (IGFs) and insulin.
Downstream signaling pathways activated by IGF1R include the Ras/MAPK pathway and PI3K/Akt pathway, contributing to cell growth and survival.
IGF1R interacts with IGFs and insulin, triggering downstream signaling pathways such as the PI3K/Akt pathway, influencing cell proliferation and survival.
There are potential therapeutic implications related to IGF1R in diseases involving growth signaling, making it a target for drug development.
Dysregulation or abnormal expression of IGF1R is associated with conditions such as cancer and developmental disorders.
Insulin-like growth factor 1 receptor (IGF1R) functions in cellular processes, primarily playing a role in growth signaling.
IGF1R contributes to the regulation of tissue development by influencing cell growth, differentiation, and survival.
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