Recombinant Human IL12B Protein (Ile23-Ser328), C-His tagged

Cat.No. : IL12B-4305H
Product Overview : Recombinant human IL12B/IL-12 p40/NKSF2 (Ile23-Ser328) fused with the C-terminal His tag was expressed in Mammalian cells.
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Source : Mammalian cells
Species : Human
Tag : His
Form : Lyophilized powder/frozen liquid
Molecular Mass : 38.14 kDa
Protein Length : Ile23-Ser328
Purity : >90% as determined by SDS-PAGE.
Notes : For research use only.
Storage : Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
Storage Buffer : Supplied as solution form in PBS, pH 7.4.
Reconstitution : Reconstitute in sterile water for a stock solution.
Shipping : They are shipped out with dry ice/blue ice unless customers require otherwise.
Gene Name : IL12B interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) [ Homo sapiens (human) ]
Official Symbol : IL12B
Synonyms : IL12B; interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40); NKSF2; interleukin-12 subunit beta; CLMF; CLMF2; cytotoxic lymphocyte maturation factor 2; p40; IL 12B; IL12; subunit p40; interleukin 12; interleukin 12 beta chain; natural killer cell stimulatory factor; 40 kD subunit; natural killer cell stimulatory factor 2; NKSF; CLMF p40; IL-12 subunit p40; IL12, subunit p40; interleukin 12, p40; interleukin-12 beta chain; NK cell stimulatory factor chain 2; cytotoxic lymphocyte maturation factor 40 kDa subunit; natural killer cell stimulatory factor, 40 kD subunit; IL-12B;
Gene ID : 3593
mRNA Refseq : NM_002187
Protein Refseq : NP_002178
MIM : 161561
UniProt ID : P29460

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Customer Reviews (3)

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Reviews
04/08/2020

    Good for cytokine assays.

    01/06/2020

      Effective in Th2 cell differentiation.

      01/12/2019

        High yield in expression.

        Q&As (10)

        Ask a question
        Could you explain the use of ChIP-seq in studying IL12B transcriptional regulation? 05/12/2021

        ChIP-seq identifies regulatory elements controlling IL12B gene expression.

        Can you elaborate on the use of reporter assays to monitor IL12B promoter activity? 05/02/2021

        Reporter assays monitor IL12B promoter activity under varying conditions.

        What methods evaluate IL12B's response to different pathogenic stimuli in primary cells? 10/30/2020

        Primary cell stimulation assays gauge IL12B response to pathogens.

        How does siRNA knockdown of IL12B elucidate its role in immune cell activation? 05/25/2020

        siRNA knockdown uncovers IL12B's role in immune cell activation pathways.

        How does recombinant protein expression and purification aid in IL12B functional studies? 04/30/2020

        Recombinant protein expression enables functional IL12B studies in vitro.

        How does co-immunoprecipitation validate IL12B's association with signaling partners? 04/12/2018

        Co-IP validates IL12B's binding to specific signaling partners.

        What techniques are employed to analyze the impact of IL12B genetic variants on protein function? 12/03/2017

        Genetic variant analysis reveals impacts on IL12B protein function.

        How does flow cytometry reveal IL12B's expression dynamics in different immune cell subsets? 10/31/2017

        Flow cytometry profiles IL12B expression across diverse immune cell types.

        What experimental approaches determine IL12B's cytokine secretion kinetics upon stimulation? 09/29/2017

        Cytokine secretion assays measure IL12B's response kinetics to stimuli.

        What are the methods to assess IL12B's protein-protein interactions in a cellular context? 08/22/2017

        Co-IP and immunoprecipitation assess IL12B's interactions with other proteins.

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