Recombinant Human IL18RAP Protein, hIgG/His-tagged
Cat.No. : | IL18RAP-17H |
Product Overview : | Recombinant human IL-18 R beta/IL-1 R7 protein (20-356aa, 576aa), fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
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Description : | The protein encoded by this gene is an accessory subunit of the heterodimeric receptor for interleukin 18 (IL18), a proinflammatory cytokine involved in inducing cell-mediated immunity. This protein enhances the IL18-binding activity of the IL18 receptor and plays a role in signaling by IL18. Mutations in this gene are associated with Crohn's disease and inflammatory bowel disease, and susceptibility to celiac disease and leprosy. Alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. |
Source : | Insect cell |
Species : | Human |
Tag : | hIgG/His |
Form : | Liquid |
Molecular Mass : | 65.4 kDa |
Protein length : | 20-356 |
AA Sequence : | FNISGCSTKKLLWTYSTRSEEEFVL FCDLPEPQKSHFCHRNRLSPKQVPE HLPFMGSNDLSDVQWYQQPSNGDPL EDIRKSYPHIIQDKCTLHFLTPGVN NSGSYICRPKMIKSPYDVACCVKMI LEVKPQTNASCEYSASHKQDLLLGS TGSISCPSLSCQSDAQSPAVTWYKN GKLLSVERSNRIVVDEVYDYHQGTY VCDYTQSDTVSSWTVRAVVQVRTIV GDTKLKPDILDPVEDTLEVELGKPL TISCKARFGFERVFNPVIKWYIKDS DLEWEVSVPEAKSIKSTLKDEIIER NIILEKVTQRDLRRKFVCFVQNSIG NTTQSVQLKEKR |
Endotoxin : | < 1 EU/μg of protein (determined by LAL method) |
Purity : | > 90% by SDS-PAGE |
Applications : | SDS-PAGE |
Storage : | Can be stored at 2 to 8 centigrade for 1 week. For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles. |
Concentration : | 0.25 mg/mL (determined by absorbance at 280nm) |
Storage Buffer : | Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol |
Gene Name : | IL18RAP interleukin 18 receptor accessory protein [ Homo sapiens (human) ] |
Official Symbol : | IL18RAP |
Synonyms : | IL18RAP; interleukin 18 receptor accessory protein; ACPL; CD218b; IL-1R7; IL18RB; CDw218b; IL-1R-7; IL-18RAcP; IL-1RAcPL; IL-18Rbeta; IL-18R-beta; interleukin-18 receptor accessory protein; CD218 antigen-like family member B; IL-18 receptor accessory protein; IL-18 receptor beta; cluster of differentiation w218b; interleukin-1 receptor 7; interleukin-18 receptor beta; EC 3.2.2.6 |
Gene ID : | 8807 |
mRNA Refseq : | NM_003853 |
Protein Refseq : | NP_003844 |
MIM : | 604509 |
UniProt ID : | O95256 |
Products Types
◆ Recombinant Protein | ||
IL18RAP-157H | Recombinant Human IL18RAP Protein, His-tagged | +Inquiry |
IL18RAP-97H | Recombinant Human IL18RAP Protein, His (Fc)-Avi-tagged | +Inquiry |
IL18RAP-8835C | Recombinant Rhesus IL18RAP protein, hFc-tagged | +Inquiry |
Il18rap-514M | Active Recombinant Mouse Il18rap, His-tagged | +Inquiry |
IL18RAP-8836C | Recombinant Rhesus IL18RAP protein, His-tagged | +Inquiry |
◆ Lysates | ||
IL18RAP-2602HCL | Recombinant Human IL18RAP cell lysate | +Inquiry |
IL18RAP-1353CCL | Recombinant Cynomolgus IL18RAP cell lysate | +Inquiry |
IL18RAP-001MCL | Recombinant Mouse IL18RAP cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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