| Cat.No. : |
IL1RL2-1983M
Optional Service: Optional requirements on this protein
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| Product Overview : |
Recombinant Mouse IL1RL2 Protein (22-338 aa) is produced by E. coli expression system. This protein is fused with a 6xHis tag at the N-terminal. Research Area: Immunology. Protein Description: Partial. |
| Description : |
Receptor for interleukin-36 (IL36A, IL36B and IL36G). After binding to interleukin-36 associates with the coreceptor IL1RAP to form the interleukin-36 receptor complex which mediates interleukin-36-dependent activation of NF-kappa-B, MAPK and other pathways. The IL-36 signaling system is thought to be present in epithelial barriers and to take part in local inflammatory response; it is similar to the IL-1 system. Seems to be involved in skin inflammatory response by induction of the IL-23/IL-17/IL-22 pathway. |
| Source : |
E. coli |
| Species : |
Mouse |
| Tag : |
His |
| Form : |
Tris-based buffer,50% glycerol |
| Molecular Mass : |
40.0 kDa |
| Protein length : |
22-338 aa |
| AA Sequence : |
DTCEDIFMHN VIISEGQPFP FNCTYPPETN GAVNLTWYKT PSKSPVSNNR HLRVHQDQTW ILFLPLTLED SGIYQCVIRN AHNCYQIAVN LTVLKNHWCD SSMEGSPVNS PDVYQQILPI GKSGSLNCHL YFPESCALDS IKWYKGCEEI KAGKKYSPSG AKLLVNNVAV EDGGSYACSA RLTHLGRHFT IRNYIAVNTK EVEYGRRIPN ITYPKNNSIE VPLGSTLIVN CNITDTKENT NLRCWRVNNT LVDDYYKDSK RIQEGIETNV SLRDQIRYTV NITFLKVKME DYGRPFTCHA GVSAAYIILI YPVPDFR |
| Purity : |
> 90% as determined by SDS-PAGE. |
| Notes : |
Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week. |
| Storage : |
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade. |
| Concentration : |
A hardcopy of COA with reconstitution instruction is sent along with the products. |
| Figure : |
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
