Recombinant Human IL21 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: IL21-2220H
• Product Overview: IL21 MS Standard C13 and N15-labeled recombinant protein (NP_068575) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a member of the common-gamma chain family of cytokines with immunoregulatory activity. The encoded protein plays a role in both the innate and adaptive immune responses by inducing the differentiation, proliferation and activity of multiple target cells including macrophages, natural killer cells, B cells and cytotoxic T cells. Dysregulation of this gene plays a role in multiple immune-mediated diseases including lupus, psoriasis and chronic inflammatory diseases. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 18.5 kDa
• AA Sequence: MRSSPGNMERIVICLMVIFLGTLVH KSSSQGQDRHMIRMRQLIDIVDQLK NYVNDLVPEFLPAPEDVETNCEWSA FSCFQKAQLKSANTGNNERIINVSI KKLKRKPPSTNAGRRQKHRLTCPSC DSYEKKPPKEFLERFKSLLQKMIHQ HLSSRTHGSEDSTRTRPLEQKLISE EDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: IL21 interleukin 21 [ Homo sapiens (human) ]
• Official Symbol: IL21
• Synonyms: IL21; interleukin 21; interleukin-21; IL 21; Za11; interleukin-21 isoform; IL-21
• Gene ID: 59067
• mRNA Refseq: NM_021803
• Protein Refseq: NP_068575
• MIM: 605384
• UniProt ID: Q9HBE4