Recombinant Human IL2RA Protein, Fc-tagged, FITC conjugated

Cat.No. : IL2RA-636HF
Product Overview : FITC conjugated recombinant human IL2RA α chain (NP_000408.1) precursor (Met 1-Cys 213), fused with the Fc region of human IgG1 at the C-terminus, was produced in Human Cell.
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Source : HEK293
Species : Human
Tag : Fc
Form : Lyophilized
Molecular Mass : The mature recombinant human IL2Rα/Fc is a disulfide-linked homodimeric protein generated by proteolytic removal of the signal peptide. The reduced monomer consists of 430 amino acids and has a predicted molecular mass of 48.5 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rhIL2Rα/Fc monomer is approximately 72 kDa due to glycosylation.
Endotoxin : < 1.0 EU/ μg of the protein as determined by the LAL method.
Characteristic : Disulfide-linked homodimer
Labeled with FITC via amines
Excitation source: 488 nm spectral line, argon-ion laser
Excitation Wavelength: 488 nm
Emission Wavelength: 535 nm
Stability : Samples are stable for up to 12 months from date of receipt at -70 centigrade.
Storage : Store it under sterile conditions at -20 to -70 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Storage Buffer : Lyophilized from sterile PBS, pH 7.4
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution. Centrifuge the vial at 4 centigrade before opening to recover the entire contents.
Gene Name : IL2RA interleukin 2 receptor, alpha [ Homo sapiens ]
Official Symbol : IL2RA
Gene ID : 3559
mRNA Refseq : NM_000417
Protein Refseq : NP_000408
MIM : 147730
UniProt ID : P01589

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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Is there any adverse effect of IL2RA combined with other drugs? 12/10/2022

The combination of IL2RA and other drugs may produce nausea, vomiting, rash and other adverse reactions, should be monitored.

How often is IL2RA used? 01/11/2022

The frequency of use of IL2RA depends on the specific situation of the patient, and is generally used 1-3 times per week.

Whether there is an effect of IL2RA? 12/17/2021

IL2RA, in the right dosage and frequency of use, can significantly relieve symptoms of diseases such as autoimmune diseases and organ transplant rejection.

Can IL2RA treat cancer? 05/18/2021

Can assist in the treatment of some types of malignant tumors, but it is not a complete cure for cancer.

How effective is IL2RA treatment? 04/07/2020

The effective rate of IL2RA therapy depends on many factors such as the type of disease, the patient's condition and the treatment regimen, and the effective rate is generally between 50% and 90%.

What are the indications for IL2RA? 01/09/2020

Indications of IL2RA include a variety of autoimmune diseases, organ transplant rejection and malignant tumors.

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09/29/2022

    Structural stability of IL2RA, that is, whether it can maintain its structural integrity and functional activity under different conditions such as temperature, pH value and storage time, HPLC, CD spectroscopy and other techniques can be used to evaluate the stability. -

    06/05/2021

      Solubility and stability of IL2RA in physiological buffers to ensure its reliability in practical applications. -

      03/14/2019

        To evaluate whether IL2RA has biological activity, we can verify its IL-2 binding ability and signal transduction ability through cell experiments, which are the key functions of IL2RA. -

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