Recombinant Human IL33, His-tagged

• Cat.No.: IL33-59H
• Product Overview: Recombinant Human IL33 (aa 1-270), fused at the C-terminus to a His-tag, was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-270 a.a.
• Description: IL33 (MIM 608678) is a member of the IL1 (see MIM 147760) family that potently drives production of T helper-2 (Th2)-associated cytokines (e.g., IL4; MIM 147780). IL33 is a ligand for IL33R (IL1RL1; MIM 601203), an IL1 family receptor that is selectively expressed on Th2 cells and mast cells.
• Form: Liquid. 0.2µm-filtered solution in 55mM TRIS-HCl, pH 8.2, containing 150mM sodium chloride.
• Endotoxin: <1.0EU/µg purified protein (LAL test)
• Purity: ≥90% (SDS-PAGE)
• Storage: -20°C
• Concentration: 0.25mg/ml

Gene Information

• Gene Name: IL33 interleukin 33 [ Homo sapiens (human) ]
• Official Symbol: IL33
• Synonyms: IL33; DVS27; IL1F11; NF-HEV; NFEHEV; C9orf26; RP11-575C20.2; interleukin 33; interleukin-33; IL-33; IL-1F11; DVS27-related protein; interleukin-1 family member 11; nuclear factor for high endothelial venules; nuclear factor from high endothelial venules
• Gene ID: 90865
• mRNA Refseq: NM_001199640
• Protein Refseq: NP_001186569
• MIM: 608678
• UniProt ID: O95760
• Chromosome Location: 9p24.1
• Pathway: Cytosolic DNA-sensing pathway; Influenza A
• Function: cytokine activity; protein binding