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Recombinant Human IL34 protein, Fc-tagged

Cat.No. : IL34-215H
Product Overview : Recombinant Human IL34(Asn21-Pro242) fused with the Fc region of mouse IgG2a at N-terminal was expressed in CHO.
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  • Gene Information
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Description : Interleukin-34 is a cytokine that promotes the differentiation and viability of monocytes and macrophages through the colony-stimulating factor-1 receptor (CSF1R; MIM 164770) (Lin et al., 2008 [PubMed 18467591]).
Source : CHO
Species : Human
Tag : Fc
Form : Lyophilized from 0.2μm-filtered solution in PBS.
Molecular Mass : 51 KDa
Protein length : Asn21-Pro242
Endotoxin : <0.06 EU/μg as determined by LAL test.
Purity : >98%,by SDS-PAGE under reducing conditions.
Storage : Stable for at least 1 year after receipt when stored at -20 centigrade. Working aliquots are stable for up to 3 months. when stored at -20 centigrade.
Reconstitution : Reconstitute at 100μg/ml in sterile PBS.
Gene Name : IL34 interleukin 34 [ Homo sapiens ]
Official Symbol : IL34
Synonyms : IL34; interleukin 34; C16orf77, chromosome 16 open reading frame 77; interleukin-34; IL 34; MGC34647; IL-34; C16orf77;
Gene ID : 146433
mRNA Refseq : NM_001172771
Protein Refseq : NP_001166242
MIM : 612081
UniProt ID : Q6ZMJ4
Chromosome Location : 16q22.1
Function : cytokine activity; growth factor activity; macrophage colony-stimulating factor receptor binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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What is the effect of IL34 on tumor prognosis? 09/19/2022

There are no clear studies showing the effect of IL34 on tumor prognosis.

What are the advantages of IL34 over other treatments? 05/14/2022

Can fight disease by modulating the immune system and may have better efficacy and fewer side effects than other treatments.

What is the mechanism of action of IL34 in the treatment of tumor? 07/09/2020

May inhibit tumor growth and metastasis by enhancing immune cells' ability to attack tumor cells.

How is the clinical trial of IL34 progressing? 04/02/2020

No large-scale clinical trials have been reported, but some early studies have shown a potential therapeutic effect.

How does IL34 affect the immune system? 03/26/2020

Regulate the function of macrophages and dendritic cells and affect the immune response of the immune system.

How to evaluate the efficacy of IL34? 01/31/2019

The evaluation of the efficacy of IL34 usually requires a comprehensive evaluation of clinical symptoms, biochemical indicators, imaging and other indicators.

Customer Reviews (3)

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Reviews
05/10/2021

    IL34 has shown good biocompatibility and safety in related experiments.

    01/19/2020

      When using IL34 for experiments, the experimental conditions and results are highly repeatable.

      10/24/2019

        Quality is stable and reliable, with no significant differences between batches.

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