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Recombinant Human IL3RA Protein, His-Avi-tagged, Biotinylated
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Cat.No. : | IL3RA-156H Optional Service: Optional requirements on this protein |
Product Overview : | Biotinylated Human IL-3 R alpha, His,Avitag is expressed from human 293 cells (HEK293). It contains AA Thr 19 - Arg 305 (Accession # P26951-1). |
Description : | Interleukin 3 receptor alpha (low affinity) (IL3RA), also known as CD123 (Cluster of Differentiation 123) is a 70-kD glycoprotein member of the hematopoietin receptor superfamily. This protein associates with a beta subunit common to the receptors for IL-5 and granulocyte-macrophage colony-stimulating factor (GM-CSF) to form a high-affinity receptor for IL-3. The interleukin-3 receptor α chain (CD123) has been identified as a potential immunotherapeutic target because it is overexpressed in AML compared with normal hematopoietic stem cells. |
Source : | HEK293 |
Species : | Human |
Tag : | His-Avi |
Predicted N Terminal : | Thr 19 |
Form : | Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization. |
Molecular Mass : | The protein has a calculated MW of 36.7 kDa. The protein migrates as 50-65 kDa under reducing (R) condition (SDS-PAGE). |
Protein length : | Thr 19 - Arg 305 |
Endotoxin : | Less than 1.0 EU per μg by the LAL method. |
Purity : | >95% as determined by SDS-PAGE. |
Storage : | For long term storage, the product should be stored at lyophilized state at -20°C or lower. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: -20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4ºC before opening to recover the entire contents. |
SDS-PAGE : |
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SEC-MALS : |
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Bioactivity-ELISA : |
![]() Immobilized Biotinylated Human IL-3 R alpha, His,Avitag at 1 μg/mL (100 μL/well) on streptavidin precoated (0.5 μg/well) plate, can bind Anti-IL-3 R alpha Antibody, Human IgG1 with a linear range of 0.2-1 ng/mL. |
Gene Name : | IL3RA interleukin 3 receptor, alpha (low affinity) [ Homo sapiens ] |
Official Symbol : | IL3RA |
Synonyms : | IL3R; IL3RA; IL-3Ra; IL-3R-alpha; IL3RAY; IL3RX; IL3RY; CD123 antigen; CD123; hIL3Ra; hIL-3Ra; MGC34174; IL-3 R alpha |
Gene ID : | 3563 |
mRNA Refseq : | NM_002183 |
Protein Refseq : | NP_002174 |
MIM : | 308385 |
UniProt ID : | P26951 |
◆ Recombinant Protein
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IL3RA-327H | Recombinant Human IL3RA Protein, LIgG2b Fc-tagged, low endotoxin | +Inquiry |
IL3RA-2053H | Recombinant Human IL3RA Protein, His-tagged | +Inquiry |
IL3RA-06H | Recombinant Human IL3RA Protein, C-Fc-Avi tagged, Biotinylated | +Inquiry |
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◆ Lysates
IL3RA-2433HCL | Recombinant Human IL3RA cell lysate | +Inquiry |
IL3RA-742CCL | Recombinant Canine IL3RA cell lysate | +Inquiry |
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