Recombinant Human IL3RA Protein, His-Avi-tagged, Biotinylated
Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.
|Product Overview :||Biotinylated Human IL-3 R alpha, His,Avitag is expressed from human 293 cells (HEK293). It contains AA Thr 19 - Arg 305 (Accession # P26951-1).|
|Description :||Interleukin 3 receptor alpha (low affinity) (IL3RA), also known as CD123 (Cluster of Differentiation 123) is a 70-kD glycoprotein member of the hematopoietin receptor superfamily. This protein associates with a beta subunit common to the receptors for IL-5 and granulocyte-macrophage colony-stimulating factor (GM-CSF) to form a high-affinity receptor for IL-3. The interleukin-3 receptor α chain (CD123) has been identified as a potential immunotherapeutic target because it is overexpressed in AML compared with normal hematopoietic stem cells.|
|Predicted N Terminal :||Thr 19|
|Form :||Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.|
|Molecular Mass :||The protein has a calculated MW of 36.7 kDa. The protein migrates as 50-65 kDa under reducing (R) condition (SDS-PAGE).|
|Protein length :||Thr 19 - Arg 305|
|Endotoxin :||Less than 1.0 EU per μg by the LAL method.|
|Purity :||>95% as determined by SDS-PAGE.|
|Storage :||For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.
|Reconstitution :||It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4ºC before opening to recover the entire contents.|
Immobilized Biotinylated Human IL-3 R alpha, His,Avitag at 1 μg/mL (100 μL/well) on streptavidin precoated (0.5 μg/well) plate, can bind Anti-IL-3 R alpha Antibody, Human IgG1 with a linear range of 0.2-1 ng/mL.
|Gene Name :||IL3RA interleukin 3 receptor, alpha (low affinity) [ Homo sapiens ]|
|Official Symbol :||IL3RA|
|Synonyms :||IL3R; IL3RA; IL-3Ra; IL-3R-alpha; IL3RAY; IL3RX; IL3RY; CD123 antigen; CD123; hIL3Ra; hIL-3Ra; MGC34174; IL-3 R alpha|
|Gene ID :||3563|
|mRNA Refseq :||NM_002183|
|Protein Refseq :||NP_002174|
|UniProt ID :||P26951|
◆ Recombinant Protein
|IL3RA-29795THP||Recombinant Human IL3RA protein, Fc-tagged, R-PE labeled||+Inquiry|
|Il3ra-5661MA||Recombinant Mouse Il3ra protein, Fc-tagged, APC labeled||+Inquiry|
|Il3ra-918MP||Recombinant Mouse Il3ra protein, Fc-tagged, R-PE labeled||+Inquiry|
|IL3RA-1120H||Recombinant Human IL3RA Protein (Met1-Arg305), HlgG1 Fc-tagged||+Inquiry|
|IL3RA-121HP||Recombinant Human IL3RA protein, Fc-tagged, R-PE labeled||+Inquiry|
|IL3RA-742CCL||Recombinant Canine IL3RA cell lysate||+Inquiry|
|IL3RA-2433HCL||Recombinant Human IL3RA cell lysate||+Inquiry|