"IL4R" Related Products

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Recombinant Human IL4R Protein, His-tagged

Cat.No.: IL4R-587H
Product Overview: Human IL-4 R alpha / CD124 Protein, Met 26 - His 232 (Accession # NP_000409.1) was produced in human 293 cells (HEK293).
Source: HEK293
Species: Human
Tag: His
Predicted N Terminal: Met 26
Form: Lyophilized from sterile PBS, pH7.4, 10% Trehalose.
Bio-activity: Measured by its binding ability in a functional ELISA against immobilized Human IL-4 (0.5 μg/well). The linear range is 0.01-0.1 μg/mL.
Molecular Mass: Human IL-4 R alpha, His Tag is fused with a polyhistidine tag at the C-terminus, and has a calculated MW of 24.5 kDa. The reducing protein migrates as 35-45 kDa in SDS-PAGE due to glycosylation.
Endotoxin: Less than 1.0 EU per μg by the LAL method.
Purity: >95% as determined by SDS-PAGE.
Stability: Samples are stable for up to twelve months from date of receipt at -70ºC.
Storage: Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4ºC before opening to recover the entire contents.
Gene Name: IL4R interleukin 4 receptor [ Homo sapiens ]
Official Symbol: IL4R
Synonyms: IL4R; interleukin 4 receptor; interleukin-4 receptor subunit alpha; CD124; IL-4 receptor subunit alpha; interleukin-4 receptor alpha chain; IL4RA; IL-4RA;
Gene ID: 3566
mRNA Refseq: NM_000418
Protein Refseq: NP_000409
MIM: 147781
UniProt ID: P24394
Chromosome Location: 16p12.1-p11.2
Pathway: Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Hematopoietic cell lineage, organism-specific biosystem; Hematopoietic cell lineage, conserved biosystem; IL-4 signaling Pathway, organism-specific biosystem; IL4-mediated signaling events, organism-specific biosystem; Inflammatory Response Pathway, organism-specific biosystem;
Function: insulin receptor substrate binding; interleukin-4 receptor activity; protein binding; receptor activity; receptor signaling protein activity;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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