Recombinant Human IL4R protein, His-tagged
| Cat.No. : | IL4R-2883H |
| Product Overview : | Recombinant Human IL4R protein(257-465 aa), fused to His tag, was expressed in E. coli. |
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| Source : | E. coli |
| Species : | Human |
| Tag : | His |
| Form : | The purified protein was Lyophilized from sterile PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH7.4). 5 % trehalose and 5 % mannitol are added as protectant before lyophilization. The elution buffer contain 300mM imidazole. |
| Protein length : | 257-465 aa |
| AA Sequence : | MKIKKEWWDQIPNPARSRLVAIIIQ DAQGSQWEKRSRGQEPAKCPHWKNC LTKLLPCFLEHNMKRDEDPHKAAKE MPFQGSGKSAWCPVEISKTVLWPES ISVVRCVELFEAPVECEEEEEVEEE KGSFCASPESSRDDFQEGREGIVAR LTESLFLDLLGEENGGFCQQDMGES CLLPPSGSTSAHMPWDEFPSAGPKE APPWGKEQPL |
| Purity : | 95%, by SDS-PAGE with Coomassie Brilliant Blue staining. |
| Storage : | Short-term storage: Store at 2-8°C for (1-2 weeks). Long-term storage: Aliquot and store at -20°C to -80°C for up to 3 months, buffer containing 50% glycerol is recommended for reconstitution. Avoid repeat freeze-thaw cycles. |
| Reconstitution : | Reconstitute at 0.25 µg/μl in 200 μl sterile water for short-term storage. Reconstitution with 200 μl 50% glycerol solution is recommended for longer term storage. |
| Gene Name : | IL4R interleukin 4 receptor [ Homo sapiens ] |
| Official Symbol : | IL4R |
| Synonyms : | IL4R; interleukin 4 receptor; interleukin-4 receptor subunit alpha; CD124; IL-4 receptor subunit alpha; interleukin-4 receptor alpha chain; IL4RA; IL-4RA; |
| Gene ID : | 3566 |
| mRNA Refseq : | NM_000418 |
| Protein Refseq : | NP_000409 |
| MIM : | 147781 |
| UniProt ID : | P24394 |
Products Types
| ◆ Recombinant Protein | ||
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| IL4R-177I | Active Recombinant Human IL4R Protein | +Inquiry |
| IL4R-068H | Recombinant Human IL4R Protein, C-His-tagged | +Inquiry |
| IL4R-329C | Recombinant Cynomolgus monkey IL4R Protein, His-tagged | +Inquiry |
| ◆ Lysates | ||
| IL4R-2719HCL | Recombinant Human IL4R cell lysate | +Inquiry |
| IL4R-1051RCL | Recombinant Rat IL4R cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionIL4R is a synthetic protein that mimics the IL-4 signaling pathway in nature and binds to the IL-4 receptor in cells, which can be used to study the IL-4 signaling pathway and related diseases.
Common IL4R production technologies include prokaryotic expression systems and mammalian cell expression systems.
This protein is used in tumor immunotherapy, which can promote anti-tumor immune response and enhance the anti-tumor effect of cytotoxic T lymphocytes.
It is mainly used in immunology, drug research and other fields. It is also widely used in vaccines, biotechnology, cancer treatment and so on.
IL4R is used to treat severe pheochromocytome-induced aerodoritis and was approved by the FDA as the first drug to treat this disease.
IL4R cannot generally be administered orally, and needs to be administered by injection or intravenous drip.
Customer Reviews (3)
Write a reviewEasy to attach to the surface of cells or materials. -
It has growth factor activity to promote cell growth and proliferation. -
In animals or humans caused by the prone production of antibodies. -
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