Recombinant Human IL5 protein, His-Avi-tagged, Biotinylated
Cat.No. : | IL5-051HB |
Product Overview : | Biotinylated Recombinant Human Interleukin-5 is produced by our Mammalian expression system and the target gene encoding Ile20-Ser134 is expressed with a 6His, Avi tag at the C-terminus. |
- Specification
- Gene Information
- Related Products
Description : | IL-5 is expressed in eosinophils, NK cells, TC2 CD8+ T cells, mast cells, CD45+ CD4+ T cells, gamma delta T cells and IL-1 beta activated endothelial cells. IL-5 acts as a growth and differentiation factor for both B cells and eosinophils. Relative to B cells, IL-5 appears to induce the differentiation of activated conventional B-2 cells into Ig-secreting cells. In addition, it induces the growth of B-1 progenitors as well as IgM production by B-1 cells.IL-5 appears to perform a number of functions on eosinophils. These include the down modulation of Mac-1,the upregulation of receptors for IgA and IgG,the stimulation of lipid mediator (leukotriene C4 and PAF) secretion and the induction of granule release.IL-5 also promotes the growth and differentiation of eosinophils. |
Source : | HEK293 |
Species : | Human |
Tag : | His-Avi |
Form : | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
Molecular Mass : | 18-24kDa, reducing conditions. |
Protein length : | Ile20-Ser134 |
Endotoxin : | Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
Purity : | Greater than 95% as determined by reducing SDS-PAGE. |
Storage : | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
Reconstitution : | Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
Shipping : | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below. |
Gene Name : | IL5 interleukin 5 [ Homo sapiens (human) ] |
Official Symbol : | IL5 |
Synonyms : | Interleukin-5; IL-5; B-cell differentiation factor I; Eosinophil differentiation factor; T-cell replacing factor; TRF; IL5 |
Gene ID : | 3567 |
mRNA Refseq : | NM_000879.3 |
Protein Refseq : | NP_000870.1 |
MIM : | 147850 |
UniProt ID : | P05113 |
Products Types
◆ Lysates | ||
IL5-456CCL | Recombinant Canine IL5 cell lysate | +Inquiry |
IL5-496MCL | Recombinant Mouse IL5 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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