Recombinant Human IL7R, Fc-His tagged

Cat.No. : IL7R-788H
Product Overview : Recombinant Human IL7R extracellular domain (Met 1-Gly 236) (NP_002176.2), fused with the polyhistidine-tagged Fc region of human IgG1 at the C-terminus, was produced in Human Cell.
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Source : Human Cells
Species : Human
Tag : Fc-His
Form : Lyophilized from sterile PBS, pH 7.4
Molecular Mass : The recombinant human IL7Rα/Fc is a disulfide-linked homodimer. The reduced monomer consists of 464 amino acids and has a predicted molecular mass of 53 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rh IL7Rα/Fc monomer is approximately 65-75 kDa due to glycosylation.
Endotoxin : < 1.0 eu per μg of the protein as determined by the LAL method.
Stability : Samples are stable for up to twelve months from date of receipt at -70oC.
Storage : Store it under sterile conditions at -20oC~-70oC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution. Centrifuge the vial at 4℃ before opening to recover the entire contents.
Gene Name : IL7R interleukin 7 receptor [ Homo sapiens ]
Official Symbol : IL7R
Gene ID : 3575
mRNA Refseq : NM_002185
Protein Refseq : NP_002176
MIM : 146661
UniProt ID : P16871

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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What is the prospect of recombinant IL7R in tumor immunotherapy? 11/19/2022

IL7R is a potential drug for tumor immunotherapy, which is expected to enhance anti-tumor immune response, but further research and clinical demonstration are still needed.

Is there any research showing that recombinant IL7R can be used to treat immune system failure? 09/23/2022

Recombinant IL7R can enhance the body's immune response, but there is not enough evidence to show that it can be used to treat immune system failure.

How the role of IL7R in immunotherapy? 05/05/2022

It can enhance the immune response ability of T cells and improve the immune response of the body, so as to have a therapeutic effect on immune-related diseases.

Does IL7R have synergistic effects with immune checkpoint inhibitors? 04/20/2022

There is no clear evidence that IL7R has a synergistic effect with immune checkpoint inhibitors, but this research direction deserves further exploration.

Which diseases is IL7R associated with? 08/03/2020

IL7R has been associated with immune-related diseases such as cancer, inflammatory bowel disease, and rheumatoid arthritis.

Is there any restriction on the use of IL7R? 10/13/2019

The use of IL7R is patient specific and may be subject to some limitations, such as pregnant and lactating women and patients with certain immune-related diseases.

Customer Reviews (3)

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Reviews
02/21/2022

    The pharmacodynamic parameters of IL7R were good.

    02/01/2022

      IL7R has good compatibility and stability with various excipients.

      09/30/2021

        Strong potential to desensitize specific allergens.

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