Recombinant Human IL7R Protein
Cat.No. : | IL7R-5169H |
Product Overview : | Human IL7R full-length ORF (AAH67539.1) recombinant protein without tag. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a receptor for interleukine 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukine 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in the V(D)J recombination during lymphocyte development. This protein is also found to control the accessibility of the TCR gamma locus by STAT5 and histone acetylation. Knockout studies in mice suggested that blocking apoptosis is an essential function of this protein during differentiation and activation of T lymphocytes. The functional defects in this protein may be associated with the pathogenesis of the severe combined immunodeficiency (SCID). [provided by RefSeq |
Source : | Wheat Germ |
Species : | Human |
Form : | Liquid |
Molecular Mass : | 51.5 kDa |
AA Sequence : | MTILGTTFGMVFSLLQVVSGESGYA QNGDLEDAELDDYTFSCYSQLEVNG SQHSLTCAFEDPDVNTTNLEFEICG ALVEVKCLNFRKLQEIYFIETKKFL LIGKSNICVKVGEKSLTCKKIDLTT IVKPEAPFDLSVIYREGANDFVVTF NTSHLQKKYVKVLMHDVAYRQEKDE NKWTHVNLSSTKLTLLQRKLQPAAM YEIKVRSIPDHYFKGFWSEWSPSYY FRTPEINNSSGEMDPILLTISILSF FSVALLVILACVLWKKRIKPIVWPS LPDHKKTLEHLCKKPRKNLNVSFNP ESFLDCQIHRVDDIQARDEVEGFLQ DTFPQQLEESEKQRLGGDVQSPNCP SEDVVITPESFGRDSSLTCLAGNVS ACDAPILSSSGSLDCRESGKNGPHV YQDLLLSLGTTNSTLPPPFSLQSGI LTLNPVAQGQPILTSLGSNQEEAYV TMSSFYQNQ |
Applications : | Antibody Production Functional Study Compound Screening |
Usage : | Heating may cause protein aggregation. Please do not heat this product before electrophoresis. |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 25 mM Tris-HCl of pH8.0 containing 2% glycerol. |
Gene Name : | IL7R interleukin 7 receptor [ Homo sapiens ] |
Official Symbol : | IL7R |
Synonyms : | IL7R; interleukin 7 receptor; interleukin-7 receptor subunit alpha; CD127; IL-7RA; CD127 antigen; IL-7R subunit alpha; IL-7 receptor subunit alpha; interleukin 7 receptor alpha chain; interleukin 7 receptor isoform H5-6; ILRA; IL7RA; CDW127; IL-7R-alpha; |
Gene ID : | 3575 |
mRNA Refseq : | NM_002185 |
Protein Refseq : | NP_002176 |
MIM : | 146661 |
UniProt ID : | P16871 |
Products Types
◆ Recombinant Protein | ||
IL7R-336H | Recombinant Human IL7R Protein, Fc-tagged | +Inquiry |
IL7R-2179H | Recombinant Human IL7R Protein, MYC/DDK-tagged | +Inquiry |
IL7R-01H | Active Recombinant Human IL7R Protein, His-tagged | +Inquiry |
IL7R-071H | Recombinant Human IL7R Protein, C-His-tagged | +Inquiry |
IL7R-1361H | Recombinant Human IL7R protein(Met1-Gly236), His&Avi-tagged, Biotinylated | +Inquiry |
◆ Lysates | ||
IL7R-2595HCL | Recombinant Human IL7R cell lysate | +Inquiry |
IL7R-959RCL | Recombinant Rat IL7R cell lysate | +Inquiry |
IL7R-2473MCL | Recombinant Mouse IL7R cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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