Recombinant Human ILDR2(Leu21-Glu186) Protein, C-Fc-tagged

• Cat.No.: ILDR2-105H
• Product Overview: Recombinant Human ILDR2(Q71H61)(Leu21-Glu186) Protein, fused with a Fc tag at the C-terminus, was produced in HEK293.

Specification

• Source: HEK293
• Species: Human
• Tag: Fc
• Form: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
• Molecular Mass: The recombinant Human ILDR2 Protein has a predicted molecular mass of 45.8kDa, it migrates with an apparent molecular mass of 47-52kDa under reducing conditions.
• AA Sequence: Leu21-Glu186
• Endotoxin: < 0.01 EU per μg of the protein as determined by the LAL method.
• Purity: Greater than 95% as determined by reducing SDS-PAGE.
• Storage: Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.25 mg/ml. Centrifuge the vial at 4°C before opening to recover the entire contents.
• Shipping: In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
  Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.

Gene Information

• Gene Name: ILDR2 immunoglobulin-like domain containing receptor 2 [ Homo sapiens ]
• Official Symbol: ILDR2
• Synonyms: C1orf32; dJ782G3.1; RP4-782G3.2
• Gene ID: 387597
• mRNA Refseq: NM_199351.2
• Protein Refseq: NP_955383.1
• UniProt ID: Q71H61

Reviews

10/28/2019

High clearance characteristics of this recombinant protein provide a new idea and method for the treatment of tumors, infections and other diseases.

03/07/2019

ILDR2's biological activity and high purity are truly amazing, which is why it is a trusted partner in the scientific field.

02/06/2019

The range of applications of this protein is amazing, and it can play a unique advantage in any field.

Q&As

Is ILDR2 recombinant a gene associated with ASD (Autism Spectrum Disorder)?

Experimental data show that ILDR2 is significantly correlated with ASD, but the exact mechanism and effects need to be further studied.

Does the loss of ILDR2 cause neuronal death?

There is no direct evidence that ILDR2 loss causes neuronal death, but it has been reported that ILDR2 is closely related to the distribution and expression of neurotransmitter receptors.

Are there known mutants or polymorphic genes associated with the function of ILDR2?

It has been reported that some mutants of ILDR2 are associated with neurotransmitter receptor binding and traction function.

Which cell signaling pathways are involved in ILDR2?

It has been reported that ILDR2 is associated with the Wnt/β-catenin signaling pathway, and may be involved in other cell signaling pathways, such as the Hippo signaling pathway.

In which diseases is the expression of ILDR2 changed?

ILDR2 expression is regulated or altered in a variety of diseases, including ASD, cancer, and cardiovascular disease.