Recombinant Human INMT Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human INMT Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. : INMT-6553H
Product Overview : INMT MS Standard C13 and N15-labeled recombinant protein (NP_006765) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : N-methylation of endogenous and xenobiotic compounds is a major method by which they are degraded. This gene encodes an enzyme that N-methylates indoles such as tryptamine. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream MINDY4 (aka FAM188B) gene. In rodents and other mammals such as cetartiodactyla this gene is in the opposite orientation compared to its orientation in human and other primates and this gene appears to have been lost in carnivora and chiroptera.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 28.7 kDa
AA Sequence : MKGGFTGGDE YQKHFLPRDY LATYYSFNGS PSPEAEMLKF NLECLHKTFG PGGLQGDTLI DIGSGPTIYQ VLAACDSFQD ITLSDFTDRN REELEKWLKK EPGAYDWTPA VKFACELEGN SGRWEEKEEK LRAAVKRVLK CDVHLGNPLA PAVLPLADCV LTLLAMECAC CSLDAYRAAL CNLASLLKPG GHLVTTVTLR LPSYVVGKRE FSCVALEKEE VEQAVLDAGF DIEQLLHSPQ SYSVTNAANN GVCCIVARKK PGPTRTRPLE QKLISEEDLA ANDILDYKDD DDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : INMT indolethylamine N-methyltransferase [ Homo sapiens (human) ]
Official Symbol : INMT
Synonyms : INMT; indolethylamine N-methyltransferase; amine N-methyltransferase; nicotine N-methyltransferase; arylamine N-methyltransferase; indolamine N-methyltransferase; aromatic alkylamine N-methyltransferase; MGC125940; MGC125941;
Gene ID : 11185
mRNA Refseq : NM_006774
Protein Refseq : NP_006765
MIM : 604854
UniProt ID : O95050

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