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Recombinant Human INPP5D Protein, Flag-tagged

Cat.No. : INPP5D-359H
Product Overview : Recombinant Human INPP5D Protein (Transcript Variant 2) is produced by HEK293T expression system. This protein is fused with a Flag tag.
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  • Gene Information
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Source : HEK293T
Species : Human
Tag : Flag
Form : PBS buffer
Molecular Mass : 133 kDa
AA Sequence : MVPCWNHGNITRSKAEELLSRTGKD GSFLVRASESISRAYALCVLYRNCV YTYRILPNEDDKFTVQASEGVSMRF FTKLDQLIEFYKKENMGLVTHLQYP VPLEEEDTGDDPEEDTESVVSPPEL PPRNIPLTASSCEAKEVPFSNENPR ATETSRPSLSETLFQRLQSMDTSGL PEEHLKAIQDYLSTQLAQDSEFVKT GSSSLPHLKKLTTLLCKELYGEVIR TLPSLESLQRLFDQQLSPGLRPRPQ VPGEANPINMVSKLSQLTSLLSSIE DKVKALLHEGPESPHRPSLIPPVTF EVKAESLGIPQKMQLKVDVESGKLI IKKSKDGSEDKFYSHKKILQLIKSQ KFLNKLVILVETEKEKILRKEYVFA DSKKREGFCQLLQQMKNKHSEQPEP DMITIFIGTWNMGNAPPPKKITSWF LSKGQGKTRDDSADYIPHDIYVIGT QEDPLSEKEWLEILKHSLQEITSVT FKTVAIHTLWNIRIVVLAKPEHENR ISHICTDNVKTGIANTLGNKGAVGV SFMFNGTSLGFVNSHLTSGSEKKLR RNQNYMNILRFLALGDKKLSPFNIT HRFTHLFWFGDLNYRVDLPTWEAET IIQKIKQQQYADLLSHDQLLTERRE QKVFLHFEEEEITFAPTYRFERLTR DKYAYTKQKATGMKYNLPSWCDRVL WKSYPLVHVVCQSYGSTSDIMTSDH SPVFATFEAGVTSQFVSKNGPGTVD SQGQIEFLRCYATLKTKSQTKFYLE FHSSCLESFVKSQEGENEEGSEGEL VVKFGETLPKLKPIISDPEYLLDQH ILISIKSSDSDESYGEGCIALRLEA TETQLPIYTPLTHHGELTGHFQGEI KLQTSQGKTREKLYDFVKTERDESS GPKTLKSLTSHDPMKQWEVTSRAPP CSGSSITEIINPNYMGVGPFGPPMP LHVKQTLSPDQQPTAWSYDQPPKDS PLGPCRGESPPTPPGQPPISPKKFL PSTANRGLPPRTQESRPSDLGKNAG DTLPQEDLPLTKPEMFENPLYGSLS SFPKPAPRKDQESPKMPRKEPPPCP EPGILSPSIVLTKAQEADRGEGPGK QVPAPRLRSFTCSSSAEGRAAGGDK SQGKPKTPVSSQAPVPAKRPIKPSR SEINQQTPPTPTPRPPLPVKSPAVL HLQHSKGRDYRDNTELPHHGKHRPE EGPPGPLGRTAMQTRTRPLEQKLIS EEDLAANDILDYKDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Gene Name : INPP5D inositol polyphosphate-5-phosphatase, 145kDa [ Homo sapiens ]
Official Symbol : INPP5D
Synonyms : INPP5D; hp51CN; SHIP; SHIP-1; p150Ship; SHIP1; SIP-145; MGC104855; MGC142140; MGC142142;
Gene ID : 3635
mRNA Refseq : NM_001017915
Protein Refseq : NP_001017915
MIM : 601582
UniProt ID : Q92835

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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Can you provide information on the molecular structure of INPP5D? 08/24/2019

INPP5D has specific domains that are responsible for its phosphatase activity, and understanding its structural details is important for comprehending its function in inositol phosphate metabolism.

What is INPP5D? 06/15/2019

INPP5D is an enzyme involved in the dephosphorylation of inositol phosphates, specifically in the conversion of inositol 1,3,4,5-tetrakisphosphate (IP4) to inositol 1,3,4-trisphosphate (IP3).

Is there any research on INPP5D as a therapeutic target? 10/28/2016

INPP5D is a subject of research, particularly in the context of cancer therapy and immunotherapy, as its modulation may affect immune cell function and cancer progression.

In which cellular processes does INPP5D play a role? 08/22/2016

INPP5D is involved in regulating processes like cell growth, immune responses, and cytoskeletal dynamics by modulating inositol phosphate signaling.

How is INPP5D activity regulated? 06/01/2016

The activity of INPP5D can be regulated through post-translational modifications and interactions with other proteins.

What are the implications of INPP5D dysregulation? 03/14/2016

Dysregulation of INPP5D can impact various cellular functions and has been associated with immune-related disorders and cancer.

What is the subcellular localization of INPP5D? 01/19/2016

INPP5D is primarily located in the cytoplasm and plays a role in regulating inositol phosphate levels within the cell.

Customer Reviews (3)

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Reviews
08/17/2021

    The responsive customer support team provided quick resolutions to any queries or issues we encountered.

    09/06/2020

      We valued the product's safety profile, which ensured the well-being of our researchers and the integrity of our experiments.

      10/08/2017

        Consistency in its performance over time made it a reliable resource for ongoing experiments.

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