Recombinant Human INS Protein, His-tagged
Cat.No. : | INS-856H |
Product Overview : | Recombinant Human INS fused with His tag at the N-terminus was produced in E. coli. |
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Species : | Human |
Source : | E.coli |
Tag : | His |
Description : | After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants. |
Form : | PBS, pH 7.4 |
AA sequence : | HHHHHHFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTS |
Gene Name | INS insulin [ Homo sapiens ] |
Official Symbol | INS |
Synonyms | INS; insulin; proinsulin; ILPR; IRDN; IDDM2; MODY10; |
Gene ID | 3630 |
mRNA Refseq | NM_000207 |
Protein Refseq | NP_000198 |
UniProt ID | P01308 |
◆ Recombinant Proteins | ||
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INS-6775C | Recombinant Chicken INS | +Inquiry |
INS-1759H | Recombinant Human INS protein, His & T7-tagged | +Inquiry |
INS-674B | Recombinant Bovine INS protein, His-KSI-tagged | +Inquiry |
INS-369C | Recombinant Cynomolgus Monkey INS Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Native Proteins | ||
INS-5435B | Native Bovine Insulin | +Inquiry |
INS-512D | Native Bovine INS | +Inquiry |
◆ Cell & Tissue Lysates | ||
INS-5195HCL | Recombinant Human INS 293 Cell Lysate | +Inquiry |
Not For Human Consumption!
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