Recombinant Human INSR protein(601-750 aa), C-hFc & C-His-tagged
Cat.No. : | INSR-2566H |
Product Overview : | Recombinant Human INSR protein(P06213)(601-750 aa), fused with C-terminal hFc and C-terminal His tag, was expressed in HEK293. |
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Source : | HEK293 |
Species : | Human |
Tag : | C-hFc & C-His |
Protein length : | 601-750 aa |
Form : | 0.15 M Phosphate buffered saline |
AASequence : | DERRTYGAKSDIIYVQTDATNPSVP LDPISVSNSSSQIILKWKPPSDPNG NITHYLVFWERQAEDSELFELDYCL KGLKLPSRTWSPPFESEDSQKHNQS EYEDSAGECCSCPKTDSQILKELEE SSFRKTFEDYLHNVVFVPRKTSSGT |
Storage : | Shipped on dry ice. Avoid repeated freeze-thaw cycles. Upon receipt, 2 days when stored at 2 to 8 °C after thawing. Up to 12 months when aliquoted and stored at -20 to -80°C. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Gene Name : | INSR insulin receptor [ Homo sapiens ] |
Official Symbol : | INSR |
Synonyms : | INSR; insulin receptor; CD220; IR; HHF5; |
Gene ID : | 3643 |
mRNA Refseq : | NM_000208 |
Protein Refseq : | NP_000199 |
MIM : | 147670 |
UniProt ID : | P06213 |
Products Types
◆ Lysates | ||
INSR-2648HCL | Recombinant Human INSR cell lysate | +Inquiry |
INSR-474HCL | Recombinant Human INSR cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-1607 | INSR Internalization Assay Kit | +Inquiry |
Kit-1605 | U2OS INSR Bioassay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Customer Reviews (3)
Write a reviewThe compatibility with a range of lab equipment streamlined experimental procedures, saving both time and effort.
The product's support in the form of educational resources positively impacted the learning curve for our researchers.
The proactive engagement with customer insights contributed to the product's ongoing relevance in the scientific community.
Q&As (7)
Ask a questionMalfunction or dysregulation of the insulin receptor (INSR) can lead to disturbances in metabolic health, contributing to conditions like diabetes.
INSR regulates glucose metabolism by facilitating the cellular uptake of glucose in response to insulin.
The insulin receptor (INSR) is prominently expressed in tissues such as the liver, muscle, and adipose tissue.
Genetic variations or mutations in the insulin receptor (INSR) are associated with certain metabolic disorders and insulin resistance.
In diabetes, the insulin receptor (INSR) contributes to the development of insulin resistance, impairing its normal signaling functions.
The insulin receptor (INSR) protein plays a crucial role in cellular processes, particularly in mediating the effects of insulin.
Upon insulin binding, the insulin receptor (INSR) activates downstream signaling pathways, including the PI3K-AKT pathway.
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