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Recombinant Human INSR Protein, His & GST-tagged

Cat.No. : INSR-294H
Product Overview : Recombinant human INSR isoform long (NP_000199.2) cytoplasmic domain (Gly 989-Ser 1382) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
Source : Baculovirus-Insect Cells
Species : Human
Tag : His & GST
Predicted N Terminal : Met
Form : Supplied as sterile 50mM Tris, 100mM NaCl, pH 7.4, 20% gly, 0.3mM DTT.
Bio-activity : The specific activity was determined to be 45 nmol/min/mg using Poly(Ala,Glu,Lys,Tyr)6:2:5:1 as substrate.
Molecular Mass : The recombinant human INSR (989-1382)/GST chimera consists of 631 amino acids and has a calculated molecular mass of 72.3 KDa. It migrates as an approximately 70 KDa band in SDS-PAGE under reducing conditions.
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method.
Purity : >92 % as determined by SDS-PAGE.
Stability : Samples are stable for up to twelve months from date of receipt at -70ºC.
Storage : Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Gene Name : INSR insulin receptor [ Homo sapiens ]
Official Symbol : INSR
Synonyms : INSR; insulin receptor; CD220; IR; HHF5;
Gene ID : 3643
mRNA Refseq : NM_000208
Protein Refseq : NP_000199
MIM : 147670
UniProt ID : P06213
Chromosome Location : 19p13.3-p13.2
Pathway : Adherens junction, organism-specific biosystem; Adherens junction, conserved biosystem; Aldosterone-regulated sodium reabsorption, organism-specific biosystem; Aldosterone-regulated sodium reabsorption, conserved biosystem; IRS activation, organism-specific biosystem; IRS-mediated signalling, organism-specific biosystem; IRS-related events, organism-specific biosystem;

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