Recombinant Human Intercellular Adhesion Molecule 2

• Cat.No.: ICAM2-1626H

Specification

• Species: Human
• Source: Mammalian Cells
• Tag: Non
• Description: Intercellular adhesion molecule 2 (ICAM2), also known as CD102 (Cluster of Differentiation 102), is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins that bind to the leukocyte adhesion LFA-1 protein. This protein may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance.
• State Of Matter: Lyophilized.
• Purity: >95% by SDS Page and analyzed by silver stain.
• Endotoxin: <1.0 EU/µg as determined by the LAL method.
• Molecular Weight: The predicted molecular weight of Recombinant Human ICAM-2 is Mr 50 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 86 kDa.
• Storage And Stability: This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.

Gene Information

• Gene Name: ICAM2 intercellular adhesion molecule 2 [ Homo sapiens ]
• Synonyms: intercellular adhesion molecule 2; CD102; ICAM2; ICAM-2; CD102 antigen
• Gene ID: 3384
• mRNA Refseq: NM_000873
• Protein Refseq: NP_000864
• MIM: 146630
• UniProt ID: P13598
• Chromosome Location: 17q23-q25
• Pathway: Cell adhesion molecules (CAMs); Natural killer cell mediated cytotoxicity; Integrin cell surface interactions; Signaling in Immune system
• Function: integrin binding; protein binding