Recombinant Human Interleukin 1, Beta, His-tagged

• Cat.No.: IL1B-134H
• Product Overview: Recombinant Human Interleukin-1 beta produced inE.Coliis a single, non-glycosylated, Polypeptide chain containing 153 amino acids fragment (117-269) and having an amino-terminal hexahistidine tag. The IL-1b His is purified by proprietary chromatographic techniques

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 117-269 a.a.
• Description: Interleukin-1b is a potent pro-inflammatory cytokine produced by a wide variety of cell types including monocytes and macrophages. It displays a broad range of biological activity including activation of B and T cells in response to inflammation and the activation of endothelial cells.
• Physical Appearance: Sterile Filtered clear solution.
• Formulation: IL-1b His is supplied in 1x PBS and 50% glycerol.
• Purity: Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
• Stability: Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Please avoid freeze-thaw cycles.

Gene Information

• Gene Name: IL1B interleukin 1, beta [ Homo sapiens ]
• Synonyms: IL1B; interleukin 1, beta; IL-1; IL1F2; IL1-BETA; catabolin; preinterleukin 1 beta; pro-interleukin-1-beta; IL-1B;IL-1 beta; Interleukin-1 beta; IL1F2
• Gene ID: 3553
• mRNA Refseq: NM_000576
• Protein Refseq: NP_000567
• MIM: 147720
• UniProt ID: P01584
• Chromosome Location: 2q14
• Pathway: Alzheimer"s disease; Cytokine-cytokine receptor interaction; Graft-versus-host disease; Hematopoietic cell; lineage; MAPK signaling pathway; Prion diseases; Toll-like receptor signaling pathway; Type I diabetes mellitus; Apoptosis
• Function: cytokine activity; growth factor activity; interleukin-1 receptor binding; protein domain specific binding