Recombinant Human Interleukin 16, His-tagged
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Cat.No. : | IL16-46H Optional Service: Optional requirements on this protein |
Product Overview : | Recombinant I Human nterleukin-16 produced inE.Coliis a single, non-glycosylated polypeptide chain containing 150 amino acids and having a molecular mass of 15 kDa. The IL-16 is fused to His-Tagged at N-Terminus. The IL-16 is purified by proprietary chromatographic techniques. |
Description : | IL-16 is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. The signaling process of IL-16 is mediated by CD4. The product of this gene undergoes proteolytic processing, which is found to yield two functional proteins. IL-16 functions exclusively attributed to the secreted C-terminal peptide, while the N-terminal product may play a role in cell cycle control. Caspase 3 is reported to be involved in the proteolytic processing of this protein. Two transcript variants encoding different isoforms have been found for this gene. IL-16 stimulates a migratory response in cd4+ lymphocytes, monocytes, and eosinophils. Also induces t-lymphocyte expression of interleukin 2 receptor. ligand for cd4. |
Source : | Escherichia Coli. |
Amino Acid Sequence : | GSSHHHHHH SSGLVPRGSH MPDLNSSTDS AASASAASDV SVESTAEATV CTVTLEKMSAGLGFSLEGGK GSLHGDKPLT INRIFKGAAS EQSETVQPGD EILQLGGTAM QGLTRFEAWN IIKALPDGPV TIVIRRKSLQ SKETTAAGDS. |
Physical Appearance : | Sterile Filtered solution at a concentration of 1mg/ml. |
Purity : | Greater than 95.0% as determined by:(a) Analysis by RP-HPLC. (b) Analysis SDS-PAGE. |
Formulation : | IL-16 His tag protein contains20mM Tris pH-8 1mM DTT & 10%glycerol. |
Storage : | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Please avoid freeze thaw cycles. |
PDB rendering based on 1i16. : |
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Gene Name : | IL16 interleukin 16 (lymphocyte chemoattractant factor) [ Homo sapiens ] |
Synonyms : | IL16; interleukin 16 (lymphocyte chemoattractant factor); LCF; IL-16; prIL-16; FLJ16806; FLJ42735; FLJ44234; HsT19289;OTTHUMP00000190849; OTTHUMP00000190850; lymphocyte chemoattractant factor; HsT19289; Pro-interleukin-16; interleukin 16; lymphocyte chemoattractant factor |
Gene ID : | 3603 |
mRNA Refseq : | NM_004513 |
Protein Refseq : | NP_004504 |
MIM : | 603035 |
UniProt ID : | Q14005 |
Chromosome Location : | 15q26.3 |
Function : | cytokine activity; protein binding |
◆ Recombinant Protein
IL16-135H | Recombinant Human IL16 Protein | +Inquiry |
Il16-1239M | Recombinant Mouse Il16 Protein, MYC/DDK-tagged | +Inquiry |
IL16-2055R | Recombinant Rhesus Macaque IL16 Protein, His (Fc)-Avi-tagged | +Inquiry |
IL16-1007C | Recombinant Chicken IL16 Protein, His-tagged | +Inquiry |
IL16-1165H | Recombinant Human IL16 Protein, His (Fc)-Avi-tagged | +Inquiry |
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◆ Native Protein
IL16-29736TH | Native Human IL16 | +Inquiry |
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◆ Lysates
IL16-5245HCL | Recombinant Human IL16 293 Cell Lysate | +Inquiry |
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IL10IL10RAIL10RBIL11IL11RAIl11ra1IL12IL12AIL12BIL12RB1IL13IL13RA1IL13RA2IL15IL15RAIL16IL17AIL17BIl17cIL17DIl17fIL17RAIL17RDIL18IL18BPIL18R1IL18RAPIl19Il1aIl1bIL1F10IL1R1Il1r2IL1RAPIL1RAPL1IL1RAPL2IL1RL1IL1RL2Il1rnIL2Il20IL20RAIL21IL21RIL22IL22BPIL22RA1IL22RA2IL23AIL24Il25IL27IL27RAIL28AIl28bIL29IL2RAIL2RBIl2rgIL3IL31IL32Il33Il34IL3RAIL4IL4RIl4raIl5IL5RAIl6IL6RIl6raIL6STIl7IL7RIL8IL9IL36AIl12rb2IL17RBIL23RIL26IL31RAIL36BIL36GIL36RNIL37IL9RIL17RCIL17REIL28RAIL4I1IL20RBIL17RELIl11ra2IL27bIL7RAIl23a&Il12b
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