Recombinant Human Interleukin 16, His-tagged IL16-46H

Recombinant Human Interleukin 16, His-tagged


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Recombinant Human Interleukin 16, His-tagged

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Cat.No. : IL16-46H Optional Service: Optional requirements on this protein
Product Overview : Recombinant I Human nterleukin-16 produced inE.Coliis a single, non-glycosylated polypeptide chain containing 150 amino acids and having a molecular mass of 15 kDa. The IL-16 is fused to His-Tagged at N-Terminus. The IL-16 is purified by proprietary chromatographic techniques.
Description : IL-16 is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. The signaling process of IL-16 is mediated by CD4. The product of this gene undergoes proteolytic processing, which is found to yield two functional proteins. IL-16 functions exclusively attributed to the secreted C-terminal peptide, while the N-terminal product may play a role in cell cycle control. Caspase 3 is reported to be involved in the proteolytic processing of this protein. Two transcript variants encoding different isoforms have been found for this gene. IL-16 stimulates a migratory response in cd4+ lymphocytes, monocytes, and eosinophils. Also induces t-lymphocyte expression of interleukin 2 receptor. ligand for cd4.
Source : Escherichia Coli.
Physical Appearance : Sterile Filtered solution at a concentration of 1mg/ml.
Purity : Greater than 95.0% as determined by:(a) Analysis by RP-HPLC. (b) Analysis SDS-PAGE.
Formulation : IL-16 His tag protein contains20mM Tris pH-8 1mM DTT & 10%glycerol.
Storage : Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Please avoid freeze thaw cycles.
PDB rendering based on 1i16. :

Gene Name : IL16 interleukin 16 (lymphocyte chemoattractant factor) [ Homo sapiens ]
Synonyms : IL16; interleukin 16 (lymphocyte chemoattractant factor); LCF; IL-16; prIL-16; FLJ16806; FLJ42735; FLJ44234; HsT19289;OTTHUMP00000190849; OTTHUMP00000190850; lymphocyte chemoattractant factor; HsT19289; Pro-interleukin-16; interleukin 16; lymphocyte chemoattractant factor
Gene ID : 3603
mRNA Refseq : NM_004513
Protein Refseq : NP_004504
MIM : 603035
UniProt ID : Q14005
Chromosome Location : 15q26.3
Function : cytokine activity; protein binding
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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