"IRAK3" Related Products

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Recombinant Human IRAK3 Protein, GST-tagged

Cat.No.: IRAK3-5051H
Product Overview: Human IRAK3 full-length ORF ( AAH57800, 1 a.a. - 596 a.a.) recombinant protein with GST-tag at N-terminal.
Description: This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
Source: Wheat Germ
Species: Human
Tag : GST
Molecular Mass: 91.3 kDa
AA Sequence: MAGNWGARGALSAHTLLFDLPPALLGELCAVLDSCDGALGWRGLAERLSSSRLDVRHIEKYVDQGKSGTRELLWSWAQKNKTIGDLLQVLQEMGHRRAIHLITNYGAVLSPSEKSYQEGGFPNILFKETANVTVDNVLIPEHNEKGVLLKSSISFQNIIEGTRNFHKDFLIGEGEIFEVYRVEIQNLTYAVKLFKQEKKMQCKKHWKRFLSELEALLLFHHPSILELAAYFTETEKFCLIYPYMRNGTLFDRLQCVGDTAPLPWHIRIGILIGISKAIHYLHNVQPCSVICGSISSANILLDDQFQPKLTDFAMAHFRSHLEHQSCTINMTSSSSKHLWYMPEEYIRQGKLSIKTDVYSFGIVIMEVLTGCRVVLDDPKHIQLRDLLRELMEKRGLDSCLSFLDKKVPPCPRNFSAKLFCLAGRCAATRAKLRPSMDEVLNTLESTQASLYFAEDPPTSLKSFRCPSPLFLENVPSIPVEDDESQNNNLLPSDEGLRIDRMTQKTPFECSQSEVMFLSLDKKPESKRNEEACNMPSSSCEESWFPKYIVPSQDLRPYKVNIDPSSEAPGHSCRSRPVESSCSSKFSWDEYEQYKKE
Applications: Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes: Best use within three months from the date of receipt of this protein.
Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name: IRAK3 interleukin-1 receptor-associated kinase 3 [ Homo sapiens ]
Official Symbol: IRAK3
Synonyms: IRAK3; interleukin-1 receptor-associated kinase 3; IRAK M; IL-1 receptor-associated kinase M; ASRT5; IRAKM; FLJ13601;
Gene ID: 11213
mRNA Refseq: NM_001142523
Protein Refseq: NP_001135995
MIM: 604459
UniProt ID: Q9Y616

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