Human IRAK3 Knockdown Cell Lysate

• Cat.No.: IRAK3-211HKCL
• Product Overview: WB-validated IRAK3 Knockdown HeLa Cell Lysate

Specification

• Species: Human
• Source: HeLa
• Tag: Non
• Description: This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants.
• Form: Cell-Tissue Lysis buffer
• Molecular Mass: 68 kDa
• Notes: Instruction of use: This knockdown cell lysate should be paired with wild-type HeLa cell lysate for use. For Western blotting, we recommend running wild-type and knockdown lysates on the same gel, and loading each well with equal volume and equal amount of total proteins.
• Storage: Store at -20 centigrade.
• Concentration: Lot-specific
• Shipping: Blue Ice
• Components: 1 vial of 100 μg WT HeLa cell lysate 1 vial of 100 μg IRAK3 KD HeLa cell lysate
• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: Apoptosis, Neurotrophin signaling pathway
• Lysate QC: RT-qPCR; Western Blotting (WB)

Gene Information

• Gene Name: IRAK3 interleukin-1 receptor-associated kinase 3 [ Homo sapiens (human) ]
• Official Symbol: IRAK3
• Synonyms: IRAK3; interleukin-1 receptor-associated kinase 3; IRAK M; IL-1 receptor-associated kinase M; ASRT5; IRAKM; FLJ13601
• Gene ID: 11213
• mRNA Refseq: NM_001142523
• Protein Refseq: NP_001135995
• MIM: 604459
• UniProt ID: Q9Y616