Recombinant Human IRF3 Protein, His-tagged IRF3-013H

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Recombinant Human IRF3 Protein, His-tagged

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Cat.No. :	IRF3-013H
Product Overview :	Recombinant full length human IRF3 protein (1-427) with a N-terminally Histidine tag was expressed in E. coli.
Description :	This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. The protein plays an important in the innate immune response against DNA and RNA viruses.
Source :	E. coli
Species :	Human
Tag :	His
Form :	50 mM HEPES, pH 8.0, 150 mM sodium chloride, and 10% glycerol
Molecular Mass :	49.6 kDa
Protein length :	1-427
Purity :	≥85% estimated by SDS-PAGE
Stability :	≥ 1 year
Storage :	Store at -80 centigrade
Shipping :	Dry ice in continental US; may vary elsewhere
SDS-PAGE analysis of IRF3. :	Lane 1: MW Markers Lane 2: IRF3 (1 µg) Lane 3: IRF3 (2 µg) Lane 4: IRF3 (4 µg)

Gene Name :	IRF3 interferon regulatory factor 3 [ Homo sapiens (human) ]
Official Symbol :	IRF3
Synonyms :	IRF3; interferon regulatory factor 3; IIAE7; interferon regulatory factor 3
Gene ID :	3661
mRNA Refseq :	NM_001197122
Protein Refseq :	NP_001184051
MIM :	603734
UniProt ID :	Q14653