Recombinant Human IRF3 Protein, His-tagged

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Recombinant Human IRF3 Protein, His-tagged

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Cat.No. : IRF3-013H
Product Overview : Recombinant full length human IRF3 protein (1-427) with a N-terminally Histidine tag was expressed in E. coli.
Description : This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. The protein plays an important in the innate immune response against DNA and RNA viruses.
Source : E. coli
Species : Human
Tag : His
Form : 50 mM HEPES, pH 8.0, 150 mM sodium chloride, and 10% glycerol
Molecular Mass : 49.6 kDa
Protein length : 1-427
Purity : ≥85% estimated by SDS-PAGE
Stability : ≥ 1 year
Storage : Store at -80 centigrade
Shipping : Dry ice in continental US; may vary elsewhere
SDS-PAGE analysis of IRF3. :

Lane 1: MW Markers
Lane 2: IRF3 (1 µg)
Lane 3: IRF3 (2 µg)
Lane 4: IRF3 (4 µg)

Gene Name : IRF3 interferon regulatory factor 3 [ Homo sapiens (human) ]
Official Symbol : IRF3
Synonyms : IRF3; interferon regulatory factor 3; IIAE7; interferon regulatory factor 3
Gene ID : 3661
mRNA Refseq : NM_001197122
Protein Refseq : NP_001184051
MIM : 603734
UniProt ID : Q14653
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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