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Recombinant Human IRF4 Protein, Myc/DDK-tagged, C13 and N15-labeled

Cat.No. : IRF4-3565H
Product Overview : IRF4 MS Standard C13 and N15-labeled recombinant protein (NP_002451) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
  • Specification
  • Gene Information
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Description : The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 51.8 kDa
AA Sequence : MNLEGGGRGGEFGMSAVSCGNGKLR QWLIDQIDSGKYPGLVWENEEKSIF RIPWKHAGKQDYNREEDAALFKAWA LFKGKFREGIDKPDPPTWKTRLRCA LNKSNDFEELVERSQLDISDPYKVY RIVPEGAKKGAKQLTLEDPQMSMSH PYTMTTPYPSLPAQQVHNYMMPPLD RSWRDYVPDQPHPEIPYQCPMTFGP RGHHWQGPACENGCQVTGTFYACAP PESQAPGVPTEPSIRSAEALAFSDC RLHICLYYREILVKELTTSSPEGCR ISHGHTYDASNLDQVLFPYPEDNGQ RKNIEKLLSHLERGVVLWMAPDGLY AKRLCQSRIYWDGPLALCNDRPNKL ERDQTCKLFDTQQFLSELQAFAHHG RSLPRFQVTLCFGEEFPDPQRQRKL ITAHVEPLLARQLYYFAQQNSGHFL RGYDLPEHISNPEDYHRSIRHSSIQ ETRTRPLEQKLISEEDLAANDILDY KDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
Gene Name : IRF4 interferon regulatory factor 4 [ Homo sapiens (human) ]
Official Symbol : IRF4
Synonyms : IRF4; interferon regulatory factor 4; MUM1; LSIRF; multiple myeloma oncogene 1; lymphocyte-specific interferon regulatory factor; NF-EM5;
Gene ID : 3662
mRNA Refseq : NM_002460
Protein Refseq : NP_002451
MIM : 601900
UniProt ID : Q15306

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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